pathways in the muscle. Dephosphorylation and activation of the transcription factor NFAT (isoform c1), as well as the subsequent nuclear translocation, play an important role in the formation of the slow [...] slow fiber-type-specific gene program. In addition to dephosphorylation, we could show that NFATc1 is altered by further posttranslational modifications (PMTs). Furthermore, mitogen-activated protein kinases [...] muscle wasting in old age, which leads to muscle weakness and a tendency to fall. Scientific questions: 1) Studies on the physiological function of MAPK-activated protein kinases 2 and 2 (MK2/3) in the skellet

well as restriction, ligation and transformation, two rooms of our S1 laboratory are equipped for genetic engineering work at safety level 1. CRISPR/Cas9 technology, gene expression and promoter activity studies [...] from BioTek. For the cultivation of cell lines, primary cells and iPS cells we have a fully equipped S1 laboratory with sterile workbenches, incubators, centrifuge, microscope and live cell imager. For cloning

Matinmehr Tel: +49 511 532 -2630 Fax: +49 511 532-161215 address: 30625 Hannover, Carl-Neuberg-Str.1, Germany Building J03, level 03, room 1283 Career 1999 Diplomarbeit FH Hamburg bei Prof. Dr. Wacker [...] an Muskelfasern aus M. soleus-Biopsien von HCM-Patienten. Publication Myosin essential light chain 1sa decelerates actin and thin filament gliding on β-myosin molecules, Jennifer Osten, Maral Mohebbi, [...] ., Arias-Hidalgo M., Fernández J., Lomonte B. & Gutiérrez J. M., Scientific Reports 2021 Sep 30;11(1):19452, doi: 10.1038/s41598-021-98594-5, PubMed Mechanical and kinetic properties of β-cardiac/slow

of possible health damage after SARS-CoV-2 infection? Participation in cohort 1 - athletes after Covid-19 infection Cohort 1 includes athletes aged 18 years and older with a confirmed or highly probable [...] for national squads Cohort 2 includes national squad athletes from the squad groups OK, PK, EK, NK1 and NK2, including Paralympic athletes, who present themselves at one of the participating sports medicine

sequences of consortially coordinated and internationally established nuclear genes (ATM , BRCA1 , BRCA2 , BRIP1 , CDH1 , CHEK2 , PALB2 , RAD51C , RAD51D , TP53 ). However, changes outside these gene-coding sequence [...] Moorman AV, Harrison CJ. SSBP2-CSF1R is a recurrent fusion in B-lineage acute lymphoblastic leukemia with diverse genetic presentation and variable outcome. Blood. 2021 Apr 1;137(13):1835-1838. doi: 10.1182/blood [...] harboring a deletion in the genomic locus of the sterile alpha motif and HD domain containing protein 1 (SAMHD1). Stem Cell Res. 2020 Mar;43:101697. doi: 10.1016/j.scr.2019.101697. Epub 2020 Jan 9. PMID: 32062129

model for mortality and cardiovascular outcomes in older adults taking into account AZGP1. Sci Rep. 2021 Jun 3;11(1):11792. Haddad G, Kölling M, Wegmann UA, Dettling A, Seeger H, Schmitt R, Soerensen-Zender [...] emeinschaft PI: SCHM 2146/11-1, 2022-2025 Senolyse bei Nierenerkrankung: Therapeutisches Potential und Risiken Sponsor: Deutsche Forschungsgemeinschaft PI: SCHM 2146/10-1, 2020-2024 Open positions and [...] Sörensen-Zender I, Rong S, Haller H, Schmitt R. The Therapeutic Potential of Zinc-Alpha2-Glycoprotein (AZGP1) in Fibrotic Kidney Disease. Int J Mol Sci. 2022 Jan 7;23(2):646. Liao CM, Wulfmeyer VC, Swallow M,

Exception time: 0.1 to 4 seconds X-ray control area: Double focus standing anode tube Image intensifier tube: 17/10 cm or 23/15 cm, caesium - iodide Magnification: 1.5x Fluoroscopy grid: Pb 8/1 40 Fine balance [...] machine Technical data: Maximum load: 100 kN Test temperature: -70°C to +350°C Frequency range from 1 to 10 Hz Distance between the clamps 562 mm Drive unit hydraulic system Application: Tension, compression [...] Measuring resolution/readability: 0.01mg Reproducibility <±mg 0.015/0.025 Linearity deviation <±mg 0.1 Max. Range: 230g Measuring time (typical): 8s Operating temperature range +10 ... +30 °C Fully automatic

School Carl-Neuberg-Strasse 1 30625 Hannover Principal Coordinating Investigator : Prof. Dr. med. Thomas Skripuletz Clinic for Neurology Hannover Medical School Carl-Neuberg-Strasse 1 30625 Hannover Trial protocol [...] print. Erratum in: JAMA Neurol. 2025 Jun 1;82(6):630. doi: 10.1001/jamaneurol.2025.1019. Combined treatment with allogeneic Epstein-Barr- and human polyomavirus 1 specific T-cells in progres-sive multifocal [...] Maecker-Kolhoff B, Eiz-Vesper B. J Clin Immunol. 2022 Apr;42(3):546-558. doi: 10.1007/s10875-021-01205-1. Epub 2022 Jan 6. Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell

BURDETT L, YEAGER M, KORDE LA, MAI PL, PFEIFFER R, GREENE MH. Variants in or near KITLG, BAK1, DMRT1, and TERT-CLPTM1L predispose to familial testicular germ cell tumor. J Med Genet. 2011 Jul;48(7):473-6. doi: [...] band 7q22 and evaluation as a candidate myeloid tumor suppressor. Blood. 2002 Jan 1;99(1):372-4. doi: 10.1182/blood.v99.1.372. PMID: 11756194. KRATZ CP, EMERLING BM, DONOVAN S, LAIG-WEBSTER M, TAYLOR BR [...] the E-cadherin gene CDH1 are associated with the risk of brain tumors of neuroepithelial and epithelial origin. Acta Neuropathologica 2021 Apr 30. doi: 10.1007/s00401-021-02307-1. Online ahead of print

nat. Kathrin Kowalski Adress: MHH, Institut für Molekular- und Zellphysiologie Carl-Neuberg-Straße 1, 30625 Hannover, Germany Campus, Building J03, Block 01, Floor 03, Room 1320 Telephone (+49) 511 532 [...] , Perrot, A., Francino, A., Navarro-López, F., Brenner, B., & Kraft, T. (2018). Front. Physiol. 9, 1–15. doi:10.3389/fphys.2018.00359 Scientific articles in peer-reviewed journals 2023 Nonsense mediated [...] , Perrot, A., Francino, A., Navarro-López, F., Brenner, B., & Kraft, T. (2018). Front. Physiol. 9, 1–15. doi:10.3389/fphys.2018.00359 Publication Abstracts for Lectures Burkart V., Kowalski K. , Holler