Neurooncology Center
The Neurooncology Center of the MHH deals with the diagnostic clarification and surgical, drug and, in cooperation with radiotherapy, radiotherapeutic treatment of diseases of the brain, spine and skull base at the highest level. The motto of patient care is the integrated patient-centered approach. The center meets the quality criteria set by the German Cancer Society and has been awarded the title "Neurooncology Center with Recommendation of the German Cancer Society".
Specialists inneurosurgery, neurology/medical tumor therapy, radiotherapy, neuroradiology, pathology/histology and , if required, pediatric oncology work together on an interdisciplinary basis and can draw on the latest diagnostic and therapeutic procedures for individual therapy planning. We use the latest state-of-the-art treatment methods.
What you can expect from us:
- Modern diagnostic imaging and minimally invasive image-guided interventional therapy
The individual treatment concept is determined and coordinated in the interdisciplinary tumor board . The aim is to achieve the best possible treatment outcome for the patient. This often includes drug treatment, which is offered for gliomas in the transsectorally integrated consultation hours in the neurology department of the DIAKOVERE Henriettenstift .
- Microsurgical brain tumor removal using minimally invasive surgical procedures as well as neuroendoscopy, stereotaxy, fluorescence-guided tumor dissection and neuronavigated biopsy to secure the tumor tissue
- Modern technical aids to increase surgical safety such as monitoring
- Computer-assisted surgery with intraoperative monitoring procedures
- Functional surgery while awake to be able to overgrow speech, movement and other brain functions during the procedure
- Interdisciplinary discussion of individual patients to plan an individual therapy concept
- Drug-based tumor therapy
- Therapy with alternating electrical fields, so-called TTF
First Clinical Department in Lower Saxony with the institute certification "Special Neurosurgical Oncology".
In the aftercare phase, we cooperate with our rehabilitation and sports medicine specialists as well as with a large number of rehabilitation clinics. Teams from psycho-oncology, speech therapy, physiotherapy and specialized nursing staff train our patients and their relatives during their stay in order to ensure the best possible preparation for everyday life at home. On request, we can establish contact with representatives of self-help groups to provide our patients with first-hand experience reports.
- SPECT, PET, MR spectroscopy, minimally invasive image-guided interventional therapy
- Drug-based tumor therapy
- Entire spectrum of modern high-precision radiation (incl. all methods of electron and photon radiation, head and body stereotaxy and brachytherapy)
- Oncological care advice
- New therapeutics in clinical trials
- Therapy with alternating electric fields
Current studies
Brain/central nervous system
Publications
- FOERSTER A, BRAND F, BANAN R, HUENEBURG R, WEBER CAM, EWERT W, KRONENBERG J, PREVITI C, ELYAN N, BEYER U, MARTENS H, HONG B, BRAESEN JH, ERBERSDOBLER A, KRAUSS JK, STANGEL M, SAMII A, WOLF S, PRELLER M, ARETZ S, WIESE B, HARTMANN C, WEBER RG: Rare germline variants in the E-cadherin gene CDH1 are associated with the risk of brain tumors of neuroepithelial and epithelial origin. Acta Neuropathologica 2021 Apr 30. doi: 10.1007/s00401-021-02307-1. Online ahead of print
- HONG B, LALK M, WIESE B, MERTEN R, HEISSLER HE, RAAB P, HARTMANN C, KRAUSS JK: Primary and secondary gliosarcoma: differences in treatment outcome. British Journal of Neurosurgery in press, 2021.
- AL-KRINAWE Y, ESMAEILZADEH M, HARTMANN C, KRAUSS JK, HERMANN EJ: Pediatric rosette-forming glioneuronal tumor of the septum pellucidum. Childs Nervous System 36:2867-2870, 2020.
- BANAN R, ABBETMEIER-BASSE M, HONG B, DUMITRU CA, SAHM F, NAKAMURA M, KRAUSS JK, HARTMANN C: The prognostic significance of clinicopathological features in meningiomas: microscopic brain invasion can predict patient outcome in otherwise benign meningiomas. Neuropathology and Applied Neurobiology in press, 2021. Jan 28. doi: 10.1111/nan.12700. Online ahead of print
- BANAN R, STICHEL D, BLECK A, HONG B, LEHMANN U, SUWALA A, REINHARDT A, SCHRIMPF D, BUSLEI R, STADELMANN C, EHLERT K, PRINZ M, ACKER T, SCHITTENHELM J, KAUL D, SCHWEIZER L, CAPPER D, HARTER PN, ETMINAN N, JONES DTW, PFISTER SM, HEROLD-MENDE C, WICK W, SAHM F, VON DEIMLING A, HARTMANN C, REUSS DE. Infratentorial IDH-mutant astrocytoma is a distinct subtype. Acta Neuropathol. 2020 Oct;140(4):569-581.
- ESMAEILZADEH M, HONG B, POLEMIKOS M, AL-AFIF S, HERMANN EJ, SCHEINICHEN D, VON KAISENBERG C, HILLEMANNS P, KRAUSS JK: Spinal emergency surgery during pregnancy: contemporary strategies and outcome. World Neurosurgery 139:e421-e427, 2020.
- ESMAEILZADEH M, UKSUL N, HONG B, VON KAISENBERG C, SCHEINICHEN D, LANG JM, HERMANN EJ, HILLEMANNS P, KRAUSS JK: Intracranial emergencies during pregnancy requiring urgent neurosurgical treatment. Clinical Neurology and Neurosurgery 195:105905. doi: 10.1016/j.clineuro.2020.105905, 2020.
- AKÇAKAYA MO, SARYYEVA A, HEISSLER HE, KRAUSS JK: Glial tumors and deep brain stimulation: an increasingly recognized association? Journal of Clinical Neuroscience 64:1-3, 2019.
- BERKELMANN L, BADER A, MESHKSAR S, HATIPOGLU MAJERNIK G, KRAUSS JK, SCHWABE K, MANTEUFFEL D, NGEZAHAYO A: Tumor-treating fields (TTFields): investigations on the mechanism of action by electromagnetical exposure of cells in telophase/ cytokinesis. Scientific Reports 14;9(1):7362. doi: 10.1038/s41598-019-43621-9, 2019.
- HONG B, HERMANN EJ, FEUERHAKE F, KRAUSS JK: Secondary extradural spinal manifestation of esthesioneuroblastoma. British Journal of Neurosurgery 33:594-596, 2019.
- AL MAHDI MM, KRAUSS JK, NAKAMURA M, BRANDIS A, HONG B: Early ectopic recurrence of craniopharyngioma in the cerebellopontine angle. Turkish Neurosurgery 28:313-316, 2018.
- AL-AFIF S, HATIPOGLU MAJERNIK G, HERMANN EJ, ESMAEILZADEH M, HARTMANN C, KRAUSS JK: Intracranial foreign material granulomas after cranial surgery. Acta Neurochirurgica 160:2069-2075, 2018.
- AL-AFIF, HATIPOGLU MAJERNIK G, AL-KRINAWE Y, ESMAEILZADEH M, HARTMANN C, KRAUSS JK: The role of neurosurgery in the treatment of intracranial tumor-like inflammatory lesions. World Neurosurgery Dec 13:S1878-8750(18)32803-1. doi: 10.1016/j.wneu.2018.12.003, 2018.
- HONG B, BANAN R, CHRISTIANS A, NAKAMURA M, LALK M, LEHMANN U, HARTMANN C, KRAUSS JK: Cerebellar glioblastoma: a clinical series with contemporary molecular analysis. Acta Neurochirurgica 160:2237-2248, 2018.
- HONG B, POLEMIKOS M, HEISSLER HE, HARTMANN C, NAKAMURA M, KRAUSS JK: Challenges in cerebrospinal fluid shunting in patients with glioblastoma. Fluids and Barriers of the CSN 15(1):16. doi: 10.1186/s12987-018-0101-x, 2018.
- WILD F, HARTMANN C, HEISSLER HE, HONG B, KRAUSS JK, NAKAMURA M: Surgical treatment of spinal ependymomas: experience in 49 patients. World Neurosurgery 111:703-709, 2018.
- WU Z, NAKAMURA M, KRAUSS JK, SCHWABE K, JOHN N: Intracranial rat glioma model for tumor resection and local treatment. Journal of Neuroscience Methods 299:1-7, 2018.
- BEYER U, BRAND F, MARTENS H, WEDER J, CHRISTIANS A, ELYAN N, HENTSCHEL B, WESTPHAL M, SCHACKERT G, PIETSCH T, HONG B, KRAUSS JK, SAMII A, RAAB P, DAS A, DUMITRU CA, SANDALCIOGLU IE, HAKENBERG OW, ERBERSDOBLER A, LEHMANN U, REIFENBERGER G, WELLER M, REIJNS MAM, PRELLER M, WIESE B, HARTMANN C, WEBER RG: Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis. Acta Neuropathologica 134:905-922, 2017.
- BEYER U, BRAND F, MARTENS H, WEDER J, CHRISTIANS A, ELYAN N, HENTSCHEL B, WESTPHAL M, SCHACKERT G, PIETSCH T, HONG B, KRAUSS JK, SAMII A, RAAB P, DAS A, DUMITRU CA, SANDALCIOGLU IE, HAKENBERG OW, ERBERSDOBLER A, LEHMANN U, REIFENBERGER G, WELLER M, REIJNS MAM, PRELLER M, WIESE B, HARTMANN C, WEBER RG, RARE ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis. Acta Neuropathol. 2017 Dec;134(6):905-922.
- GUENTHER F, FRANK P, NAKAMURA M, HERMANN EJ, PALMAERS T. Venous air embolism in the sitting position in cranial neurosurgery: incidence and severity according to the used monitoring. Acta Neurochir (Vienna). 2017 Feb;159(2):339-346.
- VOGT PM, METT TR, BROELSCH GF, RADTKE C, GELLRICH NC, KRAUSS JK, SAMII M, IPAKTCHI R: Interdisciplinary reconstruction of oncological resections at the skull base, scalp and facial region. Surgical Oncology 26:318-323, 2017.
- AL-AFIF S, NAKAMURA M, LENARZ T, KRAUSS JK: Transclival injury after routine transnasal rhinological surgery. Clinical Neurology and Neurosurgery 145:1-5, 2016.
- HERMANN E. Calotte tumors in children (Chapter 44), Section V: Neurooncology. Pediatric neurosurgery. Baechli, Luetschg, Messing-Juenger (Eds.), Springer, 471-475 (2016) in press
- PETRAKAKIS I, PIRAYESH A, KRAUSS JK, RAAB P, HARTMANN C, NAKAMURA M: The sellar and suprasellar region: A "hideaway" of rare lesions. Clinical aspects, imaging findings, surgical outcome and comparative analysis. Clinical Neurology and Neurosurgery 149:154-165, 2016.
- PIRAYESH A, PETRAKAKIS I, RAAB P, POLEMIKOS M, KRAUSS JK, NAKAMURA M: Petroclival meningiomas: magnetic resonance imaging factors predict tumor resectability and clinical outcome. Clinical Neurology and Neurosurgery 147:90-97, 2016.
- WICK W, ROTH P, HARTMANN C, HAU P, NAKAMURA M, STOCKHAMMER F, SABEL MC, WICK A, KOEPPEN S, KETTER R, VAJKOCZY P, EYUPOGLU I, KALFF R, PIETSCH T, HAPPOLD C, GALLDIKS N, SCHMIDT-GRAF F, BAMBERG M, REIFENBERGER G, PLATTEN M, VON DEIMLING A, MEISNER C, WIESTLER B, WELLER M; Neurooncology Working Group (NOA) of the German Cancer Society. Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide. Neuro Oncol. 2016 Nov;18(11):1529-1537.
- ABUHARBID G, ESMAEILZADEH M, HARTMANN C, HERMANN EJ, KRAUSS JK: Desmoplastic infantile astrocytoma with multiple intracranial and intraspinal localizations at presentation. Child's Nervous System 31:959-964, 2015.
- ESMAEILZADEH M, YILDIZ OE, LANG JM, WEGNER F, HAUBITZ B, FEUERHAKE F, WREDE A, BRUECK W, DENGLER R, KRAUSS JK: CLIPPERS syndrome: an entity to be faced in neurosurgery. World Neurosurgery 84:2077.e1-3, 2015.
- HERMANN EJ, ESMAEILZADEH M, ERTL P, POLEMIKOS M, RAAB P, KRAUSS JK: Endoscopic intracranial surgery enhanced by electromagnetic-guided neuronavigation in children. Child's Nervous System 31:1327-1333, 2015.
- HERMANN EJ, PETRAKAKIS I, POLEMIKOS M, RAAB P, CINIBULAK Z, NAKAMURA M, KRAUSS JK: Electromagnetic navigation-guided surgery in the semi-sitting position for posterior fossa tumors: a safety and feasibility study. Acta Neurochirurgica 157:1229-1237, 2015.
- HONG B, BIERTZ F, RAAB P, SCHEINICHEN D, ERTL P, GROSSHENNIG A, NAKAMURA M, HERMANN EJ, LANG JM, LANFERMANN H, KRAUSS JK: Normobaric hyperoxia for treatment of pneumocephalus afer posterior fossa surgery in the semisitting position: a prospective randomized controlled trial. Plos One 10(5):e0125710, 2015.
- VOGT PM, IPAKTCHI R, WEYAND B, RADTKE C, KRAUSS JK, LENARZ T: Soft tissue plastic measures for complications in the cranial region. Surgeon 86:223-237, 2015.
- ESMAEILZADEH M, MAJLESARA A, FARIDAR A, HAFEZI M, HONG B, ESMAEILNIA-SHIRVANI H, NEYAZI B, MEHRABI A, NAKAMURA M. Brain metastasis from gastrointestinal cancers: a systematic review. Int J Clin Pract. 2014 Jul;68(7):890-9.
- HONG B, KRAUSS JK, BREMER M, KARSTENS JH, HEISSLER HE, NAKAMURA M: Vestibular schwannoma microsurgery for recurrent tumors after radiation therapy or previous surgical resection. Otology and Neurotology 35:171-181, 2014.
- BORRMANN N, FRIEDRICH S, SCHWABE K, HEDRICH HJ, KRAUSS JK, KNAPP WH, NAKAMURA M, MEYER GJ, WALTE A: Systemic treatment with 4-211 Atphenylalanine enhances survival of rats with intracranial glioblastoma. Nuclear Medicine 52:212-221, 2013.
- CINIBULAK Z, KRAUSS JK, NAKAMURA M: Navigated minimally invasive presigmoidal suprabulbar infralabyrinthine approach to the jugular foramen without rerouting of the facial nerve. Neurosurgery 73 (1 Suppl Operative):ons3-ons15, 2013.
- FRIEDRICH S, SCHWABE K, GROTE M, KRAUSS JK, NAKAMURA M: Effect of systemic celecoxib on human meningioma after intracranial transplantation into nude mice. Acta Neurochirurgica 155:173-182, 2013.
- HERMANN E. AND KRAUSS J.K. Giant Pediatric Midline Tumors of the Posterior Fossa: The Combined Transventricular and Supracerebellar Technique and other Approaches. M.A. Hayat (ed.), Pediatric Cancer, Volume 4, Chapter 26: Diagnosis, Therapy, and Prognosis. Cancer 4.DOI 10.1007/978-007-6591-7 26 Springer Science+Business Media Dordrecht, 265-273 (2013)
- HONG B, HERMANN EJ, REUTER C, BRANDIS A, KRAUSS JK: Outcome of surgical decompression of spinal mass lesions in non Hodgkin's lymphoma and plasmocytoma. Clinical Neurology and Neurosurgery 115:2476-2481, 2013.
- HONG B, NAKAMURA M, HARTMANN C, BRANDIS A, GANSER A, KRAUSS JK: Delayed distal spinal metastasis in thymomas. Spine 15:E1709-1713, 2013.
- HONG B, WIESE B, BREMER M, HEISSLER HE, HEIDENREICH F, KRAUSS JK, NAKAMURA M: Multiple microsurgical resections for repeated recurrence of glioblastoma multiforme. American Journal of Clinical Oncology 36:261-268, 2013.
- FRIEDRICH S, SCHWABE K, KLEIN R, KRUSCHE CA, KRAUSS JK, NAKAMURA M: Comparative morphological and immunohistochemical study of human meningioma after intracranial transplantation into nude mice. Journal of Neuroscience Methods 205:1-9, 2012.
- STEINMANN D, MAERTENS B, JANSSEN S, WERNER M, FRUEHAUF J, NAKAMURA M, CHRISTIANSEN H, BREMER M. Hypofractionated stereotactic radiotherapy (hfSRT) after tumour resection of a single brain metastasis: report of a single-centre individualized treatment approach. J Cancer Res Clin Oncol. 2012 Sep;138(9):1523-9.
- WEHMING FM, WIESE B, NAKAMURA M, BREMER M, KARSTENS JH, MEYER A. Malignant glioma grade 3 and 4: how relevant is timing of radiotherapy? Clin Neurol Neurosurg. 2012 Jul;114(6):617-21
- WICK W, PLATTEN M, MEISNER C, FELSBERG J, TABATABAI G, SIMON M, NIKKHAH G, PAPSDORF K, STEINBACH JP, SABEL M, COMBS SE, VESPER J, BRAUN C, MEIXENSBERGER J, KETTER R, MAYER-STEINACKER R, REIFENBERGER G, WELLER M; NOA-08 STUDY GROUP OF NEURO-ONCOLOGY WORKING GROUP (NOA) OF GERMAN CANCER SOCIETY, PELS H, SCHLEGEL U, HERRLINGER U, PIETSCH T, SCHRAMM J, KREX D, SCHACKERT G, RAPP M, WILLE C, BLUEMCKE I, DIENER HC, BAEHR O, RIEGER J, FRANZ K, SEIFER V, PLATE KH, WILLE C, WESTPHAL M, HEIDENREICH F, WIESE B, BREMER M, NAKAMURA M, V DEIMLING A, KLEIN AC, PFENNING P, SCHEMMER D, WICK A, OERTEL J, KORTMANN R, CONRAD J, WIEWRODT D, SCHMIEDER K, WENZ F, BOGDAHN U, HAU P, BAMBERG M, MELMS A, DOEHNER H, HAPPOLD C, ZAUGG K. Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomized, phase 3 trial. Lancet Oncol. 2012 Jul;13(7):707-15.
- YOUNES WM, HERMANN EJ, KRAUSS JK: Cisternal trochlear nerve schwannoma: improvement of diplopia after subtotal tumor excision. British Journal of Neurosurgery 26:107-109, 2012.
- CAPELLE HH, KINFE T, KRAUSS JK: Deep brain stimulation for treatment of hemichorea-hemiballism after craniopharyngioma resection: long-term follow-up. Journal of Neurosurgery 115:966-970, 2011.
- GUTENBERG A, BRANDIS A, HONG B, GUNAWAN B, ENDERS C, SCHAEFER IM, BURGER R, OSTERTAG H, GAAB M, KRAUSS JK, FUEZESI L: Common molecular cytogenetic pathway in papillary tumors of the pineal region. Brain Pathology 21:672-677, 2011.
- HONG B, KRUSCHE CA, SCHWABE K, FRIEDRICH S, KLEIN R, KRAUSS JK, NAKAMURA M: Cyclooxygenase-2 supports tumor proliferation in vestibular schwannomas. Neurosurgery 68:1112-1117, 2011.
- HONG B, NAKAMURA M, BRANDIS A, BECKER K, KRAUSS JK: Spinal metastasis of papillary tumor of the pineal region. Clinical Neurology and Neurosurgery 113:235-238, 2011.
- KINFE T, CAPELLE HH, MIRZAYAN MJ, BOSCHERT J, WEIGEL R, KRAUSS JK: Brain tumors and neuronavigation: stereotactic versus endoscopic surgery in periventricular lesions. Acta Neurochirurgica 153:517-526, 2011.
- KUPSCH A, TAGLIATI M, VIDAILHET M, AZIZ T, KRACK P, MORO E, KRAUSS JK: Early postoperative management of DBS in dystonia: programming, response to stimulation, adverse events, medication changes, evaluations, and troubleshooting. Movement Disorders 26 (S1) :S37-S53, 2011.
- LUETJENS G, KRAUSS JK, BRANDIS A, NAKAMURA M: Bilateral sphenoorbital hyperostotic meningiomas with proptosis and visual impairment. a therapeutic challenge. Clinical Neurology and Neurosurgery 113:859-863, 2011.
- GHAEMI K, MIRZAYAN MJ, KRAUSS JK: Interdural epidermoid tumor of the cavernous sinus. Central European Neurosurgery 71:155-156, 2010.
- HONG B, HERMANN EJ, HOLLWITZ B, KLEIN R, AGARONJAN A, KRAUSS JK: Primary meningeal sarcoma with leiomyoblastic differentiation complicating pregnancy. Clinical Neurology and Neurosurgery 112:516-519, 2010.
- HONG B, HERMANN EJ, KLEIN R, KRAUSS JK, NAKAMURA M: Surgical resection of osteolytic calvarial lesions: clinicopathological features. Clinical Neurology and Neurosurgery 112:865-869, 2010.
- NAKAMURA M, KRAUSS JK: Image-guided resection of small lesions in the cavernous sinus and Meckel's cave. European Journal of Surgical Oncology 36:208-213, 2010.
- LUETJENS G, MIRZAYAN JM, BRANDIS A, KRAUSS JK: Exophytic giant cell glioblastoma of the medulla oblongata. Journal of Neurosurgery 110:589-593, 2009.
- MIRZAYAN MJ, GHARABAGHI A, SAMII M, FROEMKE C, TATAGIBA M, KRAUSS JK, ROSAHL SK: The diagnostic value of erythrocyte sedimentation rate in management of brain tumors. Neurological Research 31:514-517, 2009.
- MONTIBELLER GR, STAN AC, KRAUSS JK, NAKAMURA M: Calcifying pseudoneoplasm of the inferior colliculus: an unusual loaction for a rare tumor. Neurosurgery 65:E1005-1006, 2009.
- NAKAMURA M, STOEVER T, RODT T, MAJDANI O, LORENZ M, LENARZ T, KRAUSS JK: Neuronavigational guidance in craniofacial approaches for large paranasal tumors involving the anterior skull base and upper clival lesions. European Journal of Surgical Oncology 35:666-672, 2009.
- TSCHAN CA, MIRZAYAN MJ, STAN AC, PICHLMAIER MA, KRAUSS JK: Concomitant cardiac and cerebral leiomyosarcoma: a challenge for surgical and adjuvant therapy. The Journal of Thoracic and Cardiovascular Surgery 137:e12-14, 2009.
- BECKER H, KRAUSS JK: MRI of the cervical spine: unrecognized ependymoma of the 4th ventricle. Clinical Neuroradiology 17:239-244, 2008.
- HERMANN EJ, HATTINGEN E, KRAUSS JK, MARQUARDT G, PILATUS U, TEWS DS, FRANZ K, SETZER M, GASSER T, ZANELLA FE, SEIFERT V, LANFERMANN H: Stereotactic biopsy in gluiomas guided by 3 Tesla 1H-chemical shift imaging of choline. Stereotactic and Functional Neurosurgery 86:300-307, 2008.
- HERMANN EJ, RITTIERODT M, KRAUSS JK: Combined transventricular and supracerebellar infratentorial approach preserving the vermis in giant pediatric posterior fossa midline tumors. Neurosurgery 63: ONS Suppl 1: 30-37, 2008.
- KINFE TM, CAPELLE HH, KRAUSS JK: Impact of surgical treatment on tremor due to posterior fossa tumors. Journal of Neurosurgery 108:692-697, 2008.
- KINFE TM, TSCHAN CA, STAN AC, KRAUSS JK: Solitary fibrous tumor of the foramen of Monro. Clinical Neurology and Neurosurgery 110:404-407, 2008.
- NAKAMURA M, STRUCK M, ROSER F, VORKAPIC P, SAMII M. Olfactory groove meningiomas: clinical outcome and recurrence rates after tumor removal through the frontolateral and bifrontal approach. Neurosurgery. 2008 Jun;62(6 Suppl 3):1224-32.
- MIRZAYAN MJ, GHARABAGHI A, SAMII M, TATAGIBA M, KRAUSS JK, ROSAHL SK: Response of C-reactive protein after craniotomy for microsurgery of intracranial tumors. Neurosurgery 60:621-625, 2007.
- ROSER F, NAKAMURA M, MARTINI-THOMAS R, SAMII M, TATAGIBA M. The role of surgery in meningiomas involving the optic nerve sheath. Clin Neurol Neurosurg. 2006 Jul;108(5):470-6.
- THOME C, ZEVGARIDIS D, MATEJIC D, SOMMER C, KRAUSS JK: Juxtaposition of an epidural intraforaminal cavernous hemangioma and an intradural schwannoma. Spine 29:524-527, 2004.
- WEIGEL R, SENN P, WEIS J, KRAUSS JK: Severe complications after intrathecal methotrexate for treatment of primary central nervous system lymphoma. Clinical Neurology and Neurosurgery 106:82-87, 2004.
- WOITZIK J, SOMMER C, KRAUSS JK: Delayed manifestation of spinal metastasis: a special feature of hemangiopericytoma. Clinical Neurology and Neurosurgery 105:159-166, 2003.
- POHLE T, KRAUSS JK, BURGUNDER JM: Petroclival meningioma as a cause of ipsilateral cervicofacial dyskinesias. Journal of Neurology, Neurosurgery and Psychiatry 68:113-114, 2000.
- KALBARCZYK A, KRAUSS JK, SEILER RW: Endoscopic stereotactic surgery for intraventricular loculated empyema. Surgical Neurology 52:412-417, 1999.
- PADUCH T, BABORIE A, KRAUSS JK: Bifocal temporal ganglioglioma. Neurosurgical Review 22:112-116, 1999.
- GLOCKER FX, KRAUSS JK, DEUSCHL G, SEEGER W, LUECKING CH: Hemifacial spasm due to posterior fossa tumors: the impact of tumor location on electrophysiological findings. Clinical Neurology and Neurosurgery 100:104-111, 1998.
- BORREMANS JJ, KRAUSS JK, FANARDJIAN RV, SEEGER W: Hemichorea-hemiballism associated with an ipsilateral intraventricular cyst after resection of a meningioma. Parkinsonism & Related Disorders 2:155-159, 1996.
- KRAUSS JK, BERTALANFFY H, SCHWECHHEIMER K, MUELLER A, SEEGER W: Ventral brain stem schwannoma at the entry zone of the hypoglossal nerve. Neurochirurgia 36:66-69, 1993.
- KRAUSS JK, BRAUS DF, MOHADJER M, NOBBE F, MUNDINGER F: Evaluation of the effect of treatment on movement disorders in astrocytomas of the basal ganglia and the thalamus. Journal of Neurology, Neurosurgery and Psychiatry 56:1113-1118, 1993.
- KRAUSS JK, WAKHLOO AK, SCHEREMET R, SEEGER W: Facial myokymia and spastic paretic facial contracture due to anaplastic pontocerebellar glioma. Neurosurgery 32:1031-1034, 1993.
- KRAUSS JK, NOBBE F, WAKHLOO AK, MOHADJER M, VACH W, MUNDINGER F: Movement disorders in astrocytomas of the basal ganglia and the thalamus. Journal of Neurology, Neurosurgery and Psychiatry 22:1162-1167, 1992.
- MUNDINGER F, BRAUS DF, KRAUSS JK, BIRG W: Long-term outcome of 89 low-grade brain-stem gliomas after interstitial radiation therapy. Journal of Neurosurgery 75:740-746, 1991.
- DERLIN T, SCHULTZE-FLOREY C, WERNER RA, MOEHN N, SKRIPULETZ T, DAVID S, BEUTEL G, EDER M, ROSS TL, BENGEL FM, GANSER A, KOENECKE C. 18F-FDG PET/CT of off-target lymphoid organs in CD19-targeting chimeric antigen receptor T-cell therapy for relapsed or refractory diffuse large B-cell lymphoma. Ann Nucl Med. 2021;35:132-138.
- HUEMMERT MW, STADLER M, HAMBACH L, GINGELE S, BREDT M, WATTJES MP, GOEHRING G, VENTURINI L, MOEHN N, STANGEL M, TREBST C, GANSER A, WEGNER F, SKRIPULETZ T. Severe allo-immune antibody-associated peripheral and central nervous system diseases after allogeneic hematopoietic stem cell transplantation. Sci Rep. 2021;11:8527.
- MOEHN N, SUEHS KW, ANGELA Y, STANGEL M, IVANYI P, BEUTEL G, GUTZMER R, SKRIPULETZ T, GRIMMELMANN I. Checkpoint inhibitor induced autoimmune central nervous system disorder in patients with metastatic melanoma and Hodgkin lymphoma. Clin Exp Neuroimmunol. (in press) *equal contribution
- MOEHN N, WATTJES MP, ADAMS O, NAY S, TKACHENKO D, SALGE F, HEINE J, PARS K, HOEGLINGER G, RESPONDEK G, STANGEL M, SKRIPULETZ T, JACOBS R, SUEHS KW. PD-1 inhibitor pembrolizumab for treatment of progressive multifocal leukoencephalopathy. Ther Adv Neurol Disord 2021;14:1-13
- MOEHN N, KOENECKE C, SKRIPULETZ T. Neurotoxicity under CAR-T cell therapy (CAR: chimeric antigen receptor). DGNeurology. 2020;3:doi.org/10.1007/s42451-020-00172-y
- MOEHN N, MAHJOUB S, GUTZMER R, SATZGER I, BEUTEL G, IVANYI P, GOLPON H, WATTJES MP, STANGEL M, SKRIPULETZ T. Diagnosis and Differential Diagnosis of Neurological Adverse Events during Immune Checkpoint Inhibitor Therapy. J Oncol. 2020:8865054.
- STAHL K, SCHMIDT BMW, HOEPER MM, SKRIPULETZ T, MOEHN N, BEUTEL G, EDER M, WELTE T, GANSER A, FALK CS, KOENECKE C, DAVID S. Extracorporeal cytokine removal in severe CAR-T cell associated cytokine release syndrome. J Crit Care. 2020;57:124-129.
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- HONG B, LALK M, WIESE B, MERTEN R, HEISSLER HE, RAAB P, HARTMANN C, KRAUSS JK (2021). "Primary and secondary gliosarcoma: differences in treatment and outcome." Br J Neurosurg: 1-8.
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- PIRAYESH A, PETRAKAKIS I, RAAB P, POLEMIKOS M, KRAUSS JK, NAKAMURA M (2016). "Petroclival meningiomas: Magnetic resonance imaging factors predict tumor resectability and clinical outcome." Clin Neurol Neurosurg 147: 90-97.
- RAAB P, PILATUS U, HATTINGEN E, FRANZ K, HERMANN EJ, ZANELLA FE, LANFERMANN H (2016). "Spectroscopic Characterization of Gliosarcomas-Do They Differ From Glioblastomas and Metastases?" J Comput Assist Tomogr 40(5): 815-819.
- HERMANN EJ, PETRAKAKIS I, POLEMIKOS M, RAAB P, CINIBULAK Z, NAKAMURA M, KRAUSS JK (2015). "Electromagnetic navigation-guided surgery in the semi-sitting position for posterior fossa tumors: a safety and feasibility study." Acta Neurochir (Vienna).
- HERMANN EJ, ESMAEILZADEH M, ERTL P, POLEMIKOS M, RAAB P, KRAUSS JK (2015). "Endoscopic intracranial surgery enhanced by electromagnetic-guided neuronavigation in children." Childs Nerv Syst.
- HENKENBERENS C, FRANZKE A, RAAB P, OSCHLIES I, KLAPPER W, CHRISTIANSEN H (2014). "Primary EBV-positive Hodgkin's lymphoma of the CNS under azathioprine treatment : Case report and review of the literature." Radiation Oncol 190(9): 847-852.
- HEISS, WD, RAAB P, LANFERMANN H (2011). "Multimodality Assessment of Brain Tumors and Tumor Recurrence." Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
- KORNER S, RAAB P, BRANDIS A, WEISSENBORN K (2011). "Spontaneous regression of an intracerebral lymphoma (ghost tumor) in a liver-engrafted patient." The neurologist 17(4): 218-221.
- HATTINGEN E, DELIC O, FRANZ K, PILATUS U, RAAB P, LANFERMANN H, GERLACH R (2010). "(1)H MRSI and progression-free survival in patients with WHO grades II and III gliomas." Neurol Res 32(6): 593-602.
- RAAB P, HATTINGEN E, FRANZ K, ZANELLA FE, LANFERMANN H (2010). "Cerebral gliomas: diffusional kurtosis imaging analysis of microstructural differences." Radiology 254(3): 876-881.
- HATTINGEN E, RAAB P, FRANZ K, ZANELLA FE, LANFERMANN H, PILATUS U (2008). "Myo-inositol: a marker of reactive astrogliosis in glial tumors?" NMR Biomed 21(3): 233-241.
- HATTINGEN E, RAAB P, FRANZ K, LANFERMANN H, SETZER M, GERLACH R, ZANELLA FE, PILATUS U (2008). "Prognostic value of choline and creatine in WHO grade II gliomas." Neuroradiology 50(9): 759-767.
- RAAB P, PILATUS U, LANFERMANN H (2008). "Spectroscopy of brain tumors." Rad up2date(3): 239-255.
- BANAN R, ABBETMEIER BASSE, HONG B, DUMITRU CA, SAHM F, NAKAMURA M, KRAUSS JK, HARTMANN C. The prognostic significance of clinicopathological features in meningiomas: microscopic brain invasion can predict patient outcome in otherwise benign meningiomas. Neuropathology and Applied Neurobiology. 2021. accepted
- BANAN R, AKBARIAN A, SAMII M, SAMII A, BERTALANFFY H, LEHMANN U, HARTMANN C, BRÜNING R. Diffuse midline gliomas, H3 K27M-mutant are associated with less peritumoral edema and contrast enhancement in comparison to glioblastomas, H3 K27M-wildtype of midline structures. PLOS ONE. 2021. accepted.
- HONG B, LALK M, WIESE B, MERTEN R, HEISSLER HE, RAAB P, HARTMANN C, KRAUSS JK. Primary and secondary gliosarcoma: differences in treatment and outcome. Br J Neurosurg. 2021 Feb 4;1-8. doi: 10.1080/02688697.2021.1872773.
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- THOMAS C, FEDERICO A, SILL S, BENS S, OYEN F, NEME K, JOHANN PD, HARTMANN C, HARTMANN W, SUMERAUER D, PATERNO V, SAMII A, CORDES U, SIEBERT R, FRÜHWALD MC, PAULUS W, KOOL M, HASSELBLATT M. Atypical teratoid/rhabdoid tumor (AT/RT) with molecular features of pleomorphic xanthoastrocytoma. American Journal of Surgical Pathology. 2021. accepted.
- AL KRINAWE Y, ESMAEILZADEH M, HARTMANN C, KRAUSS JK, HERMANN EJ. Pediatric rosette-forming glioneuronal tumor of the septum pellucidum. Childs Nerv Syst. 2020 Mar 26. doi: 10.1007/s00381-020-04575-w.
- BANAN R, STICHEL D, BLECK A, HONG B, LEHMANN U, SUWALA A, REINHARDT A, SCHRIMPF D, BUSLEI R, STADELMANN C, EHLERT K, PRINZ M, ACKER T, SCHITTENHELM J, KAUL D, SCHWEIZER L, CAPPER D, HARTER P, ETMINAN N, JONES DTW, PFISTER SM, HEROLD-MENDE C, WICK W, SAHM F, DEIMLING A, HARTMANN C, REUSS DE. Infratentorial IDH- mutant astrocytoma is a distinct subtype. Acta Neuropathol. 2020 Aug 10. doi: 10.1007/s00401-020-02194-y.
- BEHLING F, BARRANTES-FREER A, BEHNES CL, STOCKHAMMER F, ROHDE V, RODRÍGUEZ-VILLAGRA O, BARBOZA MA, BRÜCK W, LEHMANN U, STADELMANN C, HARTMANN C. Expression of Olig2, Nestin, NogoA and AQP4 have no impact on overall survival in IDH-wildtype glioblastoma. PLoS One. 2020 Mar 11;15(3):e0229274.
- KIM E, SOROKIN M, KANTELHARDT S, KALASAUSKAS D, SPRANG B, FAUSS F, RINGEL F, GARAZHA A, ALBERT E, GAIFULLIN N, HARTMANN C, NAUMANN N, BIKAR S-E, GIESE A, BUZDIN A. Intratumoral heterogeneity and longitudinal changes in gene expression predict differential drug sensitivity in newly diagnosed and recurrent glioblastoma. Cancers (Basel). 2020 Feb 24;12(2).
- MYNAREK M, VON HOFF K, PIETSCH T, OTTENSMEIER H, WARMUTH-METZ M, BISON B, PFISTER S, KORSHUNOV A, SHARMA T, JAEGER N, RYZHOVA M, ZHELUDKOVA O, GOLANOV A, RUSHING EJ, HASSELBLATT M, KOCH A, SCHÜLLER U, VON DEIMLING A, SAHM F, SILL M, RIEMENSCHNEIDER MJ, DOHMEN H, MONORANU C-M, SOMMER C-M, STASZEWSKI O, MAWRIN C-M, SCHITTENHELM J, BRÜCK W, FILIPSKI K, HARTMANN C, MEINHARDT M, PIETSCHMANN K, HABERLER C, SLAVC I, GERBER NU, GROTZER NU, BENESCH M, SCHLEGEL P-G, DEINLEIN F, VON BUEREN AO, FRIEDRICH C, OBRECHT D, FLEISCHHACK G, KWIECIEN R, FALDUM A, KORTMANN R-D, KOOL M, RUTKOWSKI S. Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort. J Clin Oncol. 2020 Apr 24:JCO1903057. doi: 10.1200/JCO.19.03057.
- SCHWEIZER L, THIERFELDER F, THOMAS C, SOSCHINSKI P, SUWALA A, STICHEL D, WEFERS AK, WESSELS L, MISCH M, KIM HY, JÖDICKE R, TEICHMANN D, KAUL D, KAHN J, BOCKMAYR M, HASSELBLATT M, YOUNSI A, UNTERBERG A, KNIE B, WALTER J, AL SAFATLI D, MAY SA, JÖDICKE A, NTOULIAS G, MOSKOPP D, VAJKOCZY P, HEPPNER FL, CAPPER D, HARTMANN W, HARTMANN C, VON DEIMLING A, REUSS DE, SCHÖLER A, KOCH A. Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity. Acta Neuropathol. 2020 Sep 14. doi: 10.1007/s00401-020-02218-7.
- SIEVERS P, SILL M, BLUME C, TAUZIEDE-ESPARIAT A, SCHRIMPF D, STICHEL D, REUSS DE, DOGAN H, HARTMANN C, MAWRIN C, HASSELBLATT M, STUMMER W, SCHICK U, HENCH J, FRANK S, KETTER R, SCHWEIZER L, SCHITTENHELM J, PUGET S, BRANDNER S, JAUNMUKTANE Z, KÜSTERS B, ABDULLAEV Z, PEKMEZCI M, SNUDERL M, RATLIFF M, HEROLD-MENDE C, UNTERBERG A, ALDAPE K, ELLISON DW, WESSELING P, REIFENBERGER G, WICK W, PERRY A, VARLET P, PFISTER SM, JONES DTW, VON DEIMLING A, SAHM F. Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1. German Consortium "Aggressive Meningiomas". Acta Neuropathol. 2020 Dec 14. doi: 10.1007/s00401-020-02247-2.
- SUWALA AK, STICHEL D, SCHRIMPF D, KLOOR M, WEFERS AK, REINHARDT A, MAAS SLN, KRATZ CP, SCHWEIZER L, HASSELBLATT M, SNUDERL M, ABEDALTHAGAFI MSJ, ABDULLAEV Z, MONORANU CM, BERGMANN M, PEKRUN A, FREYSCHLAG C, ARONICA E, KRAMM CM, HINZ F, SIEVERS P, KORSHUNOV A, KOOL M, PFISTER SM, STURM D, JONES DTW, WICK W, UNTERBERG A, HARTMANN C, DODGSHUN A, TABORI U, WESSELING P, SAHM F, VON DEIMLING A, REUSS DE. Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis. Acta Neuropathol. 2020 Nov 20. doi: 10.1007/s00401-020-02243-6.
- BERGNER CG, VAN DER MEER F, WINKLER A, WRZOS C, TÜRKMEN M, VALIZADA E, FITZNER D, HAMETNER S, HARTMANN, C, PFEIFENBRING S, STOLTENBURG-DIDINGER G, BRÜCK W, NESSLER S, STADELMANN C. Microglia damage precedes major myelin breakdown in X-linked adrenoleukodystrophy and metachromatic leukodystrophy. Glia. 2019;1–14. doi.org/10.1002/glia.23598
- CHRISTIANS A, ADEL-HOROWSKI A, BANAN R, LEHMANN U, BARTELS S, BEHLING F, BARRANTES-FREER A, STADELMANN C, ROHDE V, STOCKHAMMER F, HARTMANN C. The prognostic role of IDH mutations in homogeneously treated patients with anaplastic astrocytomas and glioblastomas. Acta Neuropathol Commun. 2019 Oct 17;7(1):156.
- CHRISTIANS A, POISEL E, HARTMANN C, VON DEIMLING A, PUSCH S. Characterization of the Epithelial Membrane Protein 3 interaction network reveals a potential functional link to mitogenic signal transduction regulation. Int J Cancer. 2019 Jan 7. doi: 10.1002/ijc.32107.
- DENG MY, SILL M, STURM D, STICHEL D, WITT H, ECKER J, WITTMANN A, SCHITTENHELM J, EBINGER M, SCHUHMANN MU, FIGARELLA-BRANGER D, ARONICA E, STASZEWSKI O, PREUSSER M, HABERLER C, LAUTEN M, SCHÜLLER U, HARTMANN C, SNUDERL M, DUNHAM C, JABADO N, WESSELING P, DECKERT M, KEYVANI K, GOTTARDO N, GIANGASPERO F, VON HOFF K, ELLISON DW, PIETSCH T, HEROLD MENDE C, MILDE T, WITT O, KOOL M, KORSHUNOV A, WICK W, VON DEIMLING A, PFISTER SM, JONES DTW, SAHM F. Diffuse Glioneuronal tumor with Oligodendroglioma-like features and Nuclear Clusters (DGONC) - a molecularly-defined glioneuronal CNS tumor class displaying recurrent monosomy 14. Neuropathol Appl Neurobiol. 2019 Dec 23. doi: 10.1111/nan.12590.
- GALLI R, UCKERMANN O, SEHM T, LEIPNITZ E, HARTMANN C, SAHM F, KOCH E, SCHACKERT G, STEINER G, KIRSCH M. Identification of distinctive features in human intracranial tumors by label-free nonlinear multimodal microscopy. J Biophotonics. 2019 Jun 13:e201800465. doi: 10.1002/jbio.201800465.
- GHASEMI DR., SILL M, OKONECHNIKOV K, KORSHUNOV A, YIP S, SCHUTZ PW, SCHEIE D, KRUSE A, HARTER PN, KASTELAN M, WAGNER M, HARTMANN C, BENZEL J, MAASS KK, KHASRAW M, STRÄTER R, THOMAS C, PAULUS W, KRATZ CP, WITT H, KAWAUCHI D, HEROLD-MENDE C, SAHM F, BRANDNER S, KOOL M, JONES DTW, VON DEIMLING A, PFISTER SM, REUSS DE, PAJTLER KW. MYCN amplification drives an aggressive form of spinal ependymoma. Acta Neuropathol. 2019 Dec;138(6):1075-1089.
- HOU Y, PINHEIRO J, SAHM F, REUSS DE, SCHRIMPF D, STICHEL D, CASALINI B, KOELSCHE C, SIEVERS P, WEFERS AK, REINHARDT A, EBRAHIMI A, FERNÁNDEZ-KLETT F, PUSCH S, MEIER J, SCHWEIZER L, PAULUS W, PRINZ M, HARTMANN C, PLATE KH, REIFENBERGER G, PIETSCH T, VARLET P, PAGÈS M, SCHÜLLER U, SCHEIE D, DE STRICKER K, FRANK S, HENCH J, POLLO B, BRANDNER S, UNTERBERG A, PFISTER SM, JONES DTW, KORSHUNOV A, WICK W, CAPPER D, BLÜMCKE I, VON DEIMLING A, BERTERO L. Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA. Acta Neuropathol. 2019 Feb 13. doi: 10.1007/s00401-019-01969-2.
- ZEINER PS, PREUSSE C, GOLEBIEWSKA A, ZINKE J, IRIONDO A, MULLER A, KAOMA T, FILIPSKI K, MÜLLER-ESCHNER M, BERNATZ S, BLANK AE, BAUMGARTEN P, ILINA E, GROTE A, HANSMANN ML, VERHOFF MA, FRANZ K, FEUERHAKE F, STEINBACH JP, WISCHHUSEN J, STENZEL W, NICLOU SP, HARTER PN, MITTELBRONN M. Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas. Brain Pathol 2019 Jul;29(4):513-529. doi: 10.1111/bpa.12690. Epub 2019 Jan 15.
- REINHARDT A, STICHEL D, SCHRIMPF D, KOELSCHE C, WEFERS A, EBRAHIMI A, SIEVERS P, HUANG K, CASALINI MB, FERNÁNDEZ-KLETT F, ABIGAIL S, WELLER M, GRAMATZKI D, FELSBERG J, REIFENBERGER G, BECKER A, HANS VH, PRINZ M, STASZEWSKI O, ACKER T, DOHMEN H, HARTMANN C, PAULUS W, HESS K, BROKINKEL B, SCHITTENHELM J, BUSLEI R, DECKERT M, MAWRIN C, HEWER E, POHL U, JAUNMUKTANE Z, BRANDNER S, UNTERBERG A, HÄNGGI D, PLATTEN M, PFISTER S, WICK W, HEROLD-MENDE C, KORSHUNOV A, REUSS D, SAHM F, JONES DTW, CAPPER D, VON DEIMLING A. Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities. Acta Neuropathol Commun. 2019 Oct 28;7(1):163. doi: 10.1186/s40478-019-0801-8.
- AL-AFIF S, HATIPOGLU MAJERNIK G, HERMANN EJ, ESMAEILZADEH M, HARTMANN C, KRAUSS JK. Intracranial foreign material granulomas after cranial surgery. Acta Neurochir (Vienna). 2018 Sep 6. doi: 10.1007/s00701-018-3663-0.
- AL-AFIF S, MAJERNIK GH, AL KRINAWE Y, ESMAEILZADEH M, HARTMANN C, KRAUSS JK. The role of neurosurgery in the treatment of intracranial tumor-like inflammatory lesions. World Neurosurg. 2018 Dec 13. pii: S1878-8750(18)32803-1. doi: 10.1016/j.wneu.2018.12.003.
- BARTELS S, ADISA A, ALADELUSI T, LEMOUND J, STUCKI-KOCH A, HUSSEIN S, KREIPE H, HARTMANN C, LEHMANN U, HUSSEIN K. Molecular defects in BRAF wild-type ameloblastomas and craniopharyngiomas - differences in mutation profiles in epithelial-derived oropharyngeal neoplasms. Virchows Arch. 2018 Jun;472(6):1055-1059.
- BOISCH G, DUDA S, HARTMANN C, WEßLING H. Hypertrophic pachymeningoencephalitis associated with temporal giant cell arteritis. BMJ Case Rep. 2018 Sep 27;2018. pii: bcr-2018-225304. doi: 10.1136/bcr-2018-225304.
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- CHAO MM, THOMAY K, GOEHRING G, WLODARSKI M, PASTOR V, SCHLEGELBERGER B, SCHINDLER D, KRATZ CP, NIEMEYER C. Mutational Spectrum of Fanconi Anemia Associated Myeloid Neoplasms. Clin Padiatr. 2017 Nov;229(6):329-334. doi: 10.1055/s-0043-117046. Epub 2017 Nov 13. PMID: 29132164.
- HINZE L, MÖRICKE A, ZIMMERMANN M, JUNK S, CARIO G, DAGDAN E, KRATZ CP, CONTER V, SCHRAPPE M, STANULLA M. Prognostic impact of IKZF1 deletions in association with vincristine-dexamethasone pulses during maintenance treatment of childhood acute lymphoblastic leukemia on trial ALL-BFM 95. Leukemia. 2017 Aug;31(8):1840-1842. doi: 10.1038/leu.2017.154. Epub 2017 May 22. PMID: 28529312.
- KRATZ CP, ACHATZ MI, BRUGIÈRES L, FREBOURG T, GARBER JE, GREER MC, HANSFORD JR, JANEWAY KA, KOHLMANN WK, MCGEE R, MULLIGHAN CG, ONEL K, PAJTLER KW, PFISTER SM, SAVAGE SA, SCHIFFMAN JD, SCHNEIDER KA, STRONG LC, EVANS DGR, WASSERMAN JD, VILLANI A, MALKIN D. Cancer Screening Recommendations for Individuals with Li- Fraumeni Syndrome. Clin Cancer Res. 2017 Jun 1;23(11):e38-e45. doi:10.1158/1078-0432.CCR-17-0408. PMID: 28572266.
- KRATZ CP, IZRAELI S. Down syndrome, RASopathies, and other rare syndromes. Semin Hematol. 2017 Apr;54(2):123-128. doi: 10.1053/j.seminhematol.2017.04.008. Epub 2017 Apr 28. PMID: 28637616.
- TABORI U, HANSFORD JR, ACHATZ MI, KRATZ CP, PLON SE, FREBOURG T, BRUGIÈRES L. Clinical Management and Tumor Surveillance Recommendations of Inherited Mismatch Repair Deficiency in Childhood. Clin Cancer Res. 2017 Jun 1;23(11):e32-e37. doi: 10.1158/1078-0432.CCR-17-0574. PMID: 28572265.
- VILLANI A, GREER MC, KALISH JM, NAKAGAWARA A, NATHANSON KL, PAJTLER KW, PFISTER SM, WALSH MF, WASSERMAN JD, ZELLEY K, KRATZ CP. Recommendations for Cancer Surveillance in Individuals with RASopathies and Other Rare Genetic Conditions with Increased Cancer Risk. Clin Cancer Res. 2017 Jun 15;23(12):e83-e90. doi: 10.1158/1078-0432.CCR-17-0631. PMID: 28620009.
- WASSERMAN JD, TOMLINSON GE, DRUKER H, KAMIHARA J, KOHLMANN WK, KRATZ CP, NATHANSON KL, PAJTLER KW, PARAREDA A, REDNAM SP, STATES LJ, VILLANI A, WALSH MF, ZELLEY K, SCHIFFMAN JD. Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood. Clin Cancer Res. 2017 Jul 1;23(13):e123-e132. doi: 10.1158/1078-0432.CCR-17-0548. PMID: 28674121; PMCID: PMC5547889.
- WIMMER K, BEILKEN A, NUSTEDE R, RIPPERGER T, LAMOTTKE B, URE B, STEINMANN D, REINEKE-PLAASS T, LEHMANN U, ZSCHOCKE J, VALLE L, FAUTH C, KRATZ CP. A novel germline POLE mutation causes an early onset cancer prone syndrome mimicking constitutional mismatch repair deficiency. Fam Cancer. 2017 Jan;16(1):67-71. doi: 10.1007/s10689-016-9925-1. PMID: 27573199; PMCID: PMC5243902.
- BEIER R, SYKORA KW, WOESSMANN W, MAECKER-KOLHOFF B, SAUER M, KREIPE HH, DÖRK-BOUSSET T, KRATZ C, LAUTEN M. Allogeneic-matched sibling stem cell transplantation in a 13-year-old boy with ataxia telangiectasia and EBV-positive non-Hodgkin lymphoma. Bone Marrow Transplant. 2016 Sep;51(9):1271-4. doi: 10.1038/bmt.2016.93. Epub 2016 May 9. PMID: 27159176.
- CAVÉ H, CAYE A, STRULLU M, ALADJIDI N, VIGNAL C, FERSTER A, MÉCHINAUD F, DOMENECH C, PIERRI F, CONTET A, CACHEUX V, IRVING J, KRATZ C, CLAVEL J, VERLOES A. Acute lymphoblastic leukemia in the context of RASopathies. Eur J Med Genet. 2016 Mar;59(3):173-8. doi: 10.1016/j.ejmg.2016.01.003. Epub 2016 Feb 5. PMID: 26855057.
- KONTNY U, FRANZEN S, BEHRENDS U, BÜHRLEN M, CHRISTIANSEN H, DELECLUSE H, EBLE M, FEUCHTINGER T, GADEMANN G, GRANZEN B, KRATZ CP, LASSAY L, LEUSCHNER I, MOTTAGHY FM, SCHMITT C, STAATZ G, TIMMERMANN B, VORWERK P, WILOP S, WOLFF HA, MERTENS R. Diagnosis and Treatment of Nasopharyngeal Carcinoma in Children and Adolescents - Recommendations of the GPOH-NPC Study Group. Clin Padiatr. 2016 Apr;228(3):105-12. doi: 10.1055/s-0041-111180. Epub 2016 May 2. PMID: 27135270.
- KRATZ CP, STANULLA M, CAVÉ H. Genetic predisposition to acute lymphoblastic leukemia: Overview on behalf of the I-BFM ALL Host Genetic Variation Working Group. Eur J Med Genet. 2016 Mar;59(3):111-5. doi: 10.1016/j.ejmg.2015.10.003. Epub 2015 Dec 15. PMID: 26699264.
- PAUSTIAN L, CHAO MM, HANENBERG H, SCHINDLER D, NEITZEL H, KRATZ CP, EBELL W. Androgen therapy in Fanconi anemia: A retrospective analysis of 30 years in Germany. Pediatr Hematol Oncol. 2016 Feb;33(1):5-12. doi: 10.3109/08880018.2015.1129567. Epub 2016 Feb 22. PMID: 26900943.
- RIPPERGER T, TAWANA K, KRATZ C, SCHLEGELBERGER B, FITZGIBBON J, STEINEMANN D. Clinical utility gene card for: Familial platelet disorder with associated myeloid malignancies. Eur J Hum Genet. 2016 Aug;24(8). doi: 10.1038/ejhg.2015.278. Epub 2016 Jan 27. PMID: 26813945; PMCID: PMC4970691.
- SCHEER C, KRATZ C, WITT O, CREUTZIG U, REINHARDT D, KLUSMANN JH. Hematologic Response to Vorinostat Treatment in Relapsed Myeloid Leukemia of Down Syndrome. Pediatr Blood Cancer. 2016 Sep;63(9):1677-9. doi: 10.1002/pbc.26062. Epub 2016 May 18. PMID: 27191354.
- SCHÜTTE P, MÖRICKE A, ZIMMERMANN M, BLECKMANN K, REISMÜLLER B, ATTARBASCHI A, MANN G, BODMER N, NIGGLI F, SCHRAPPE M, STANULLA M, KRATZ CP. Preexisting conditions in pediatric ALL patients: Spectrum, frequency and clinical impact. Eur J Med Genet. 2016 Mar;59(3):143-51. doi: 10.1016/j.ejmg.2015.12.008. Epub 2015 Dec 28. PMID: 26732628.
- VOGT J, WERNSTEDT A, RIPPERGER T, PABST B, ZSCHOCKE J, KRATZ C, WIMMER K. PMS2 inactivation by a complex rearrangement involving an HERV retroelement and the inverted 100-kb duplicon on 7p22.1. Eur J Hum Genet. 2016 Nov;24(11):1598-1604. doi: 10.1038/ejhg.2016.75. Epub 2016 Jun 22. PMID: 27329736; PMCID: PMC5110070.
- WEBER ML, SCHNEIDER DT, OFFENMÜLLER S, KAATSCH P, EINSIEDEL HG, BENESCH M, CLAVIEZ A, EBINGER M, KRAMM C, KRATZ C, LAWLOR J, LEUSCHNER I, MERKEL S, METZLER M, NUSTEDE R, PETSCH S, SEEGER KH, SCHLEGEL PG, SUTTORP M, ZOLK O, BRECHT IB. Pediatric Colorectal Carcinoma is Associated With Excellent Outcome in the Context of Cancer Predisposition Syndromes. Pediatr Blood Cancer. 2016 Apr;63(4):611-7. doi: 10.1002/pbc.25839. Epub 2015 Nov 17. PMID: 26575411.
- WIMMER K, BRUGIÈRES L, DUVAL A, MULERIS M, KRATZ CP, VASEN HF. Constitutional or biallelic? Settling on a name for a recessively inherited cancer susceptibility syndrome. J Med Genet. 2016 Apr;53(4):226. doi: 10.1136/jmedgenet-2015-103249. Epub 2015 Jun 3. PMID: 26041761.
- BEIER R, MAECKER-KOLHOFF B, SYKORA KW, CHAO M, KRATZ C, SAUER MG. Minimal antileukaemic treatment followed by reduced-intensity conditioning in three consecutive children with Fanconi anaemia and AML. Bone Marrow Transplant. 2015 Mar;50(3):463-4. doi: 10.1038/bmt.2014.283. Epub 2014 Dec 22. PMID: 25531282.
- CHAO MM, KUEHL JS, STRAUSS G, HANENBERG H, SCHINDLER D, NEITZEL H, NIEMEYER C, BAUMANN I, VON BERNUTH H, RASCON J, NAGY M, ZIMMERMANN M, KRATZ CP, EBELL W. Outcomes of mismatched and unrelated donor hematopoietic stem cell transplantation in Fanconi anemia conditioned with chemotherapy only. Ann Hematol. 2015 Aug;94(8):1311-8. doi: 10.1007/s00277-015-2370-7. Epub 2015 Apr 12. PMID: 25862235.
- CHAO MM, EBELL W, BADER P, BEIER R, BURKHARDT B, FEUCHTINGER T, HANDGRETINGER R, HANENBERG H, KOEHL U, KRATZ C, KREMENS B, LANG P, MEISEL R, MUELLER I, ROESSIG C, SAUER M, SCHLEGEL PG, SCHULZ A, STRAHM B, THOL F, SYKORA KW. Consensus of German transplant centers on hematopoietic stem cell transplantation in Fanconi anemia. Clin Padiatr. 2015 May;227(3):157-65. doi: 10.1055/s-0035-1548841. Epub 2015 May 18. PMID: 25985449.
- FISCHER U, FORSTER M, RINALDI A, RISCH T, SUNGALEE S, WARNATZ HJ, BORNHAUSER B, GOMBERT M, KRATSCH C, STÜTZ AM, SULTAN M, TCHINDA J, WORTH CL, AMSTISLAVSKIY V, BADARINARAYAN N, BARUCHEL A, BARTRAM T, BASSO G, CANPOLAT C, CARIO G, CAVÉ H, DAKAJ D, DELORENZI M, DOBAY MP, ECKERT C, ELLINGHAUS E, EUGSTER S, FRISMANTAS V, GINZEL S, HAAS OA, HEIDENREICH O, HEMMRICH-STANISAK G, HEZAVEH K, HÖLL JI, HORNHARDT S, HUSEMANN P, KACHROO P, KRATZ CP, TE KRONNIE G, MAROVCA B, NIGGLI F, MCHARDY AC, MOORMAN AV, PANZER-GRÜMAYER R, PETERSEN BS, RAEDER B, RALSER M, ROSENSTIEL P, SCHÄFER D, SCHRAPPE M, SCHREIBER S, SCHÜTTE M, STADE B, THIELE R, VON DER WEID N, VORA A, ZALIOVA M, ZHANG L, ZICHNER T, ZIMMERMANN M, LEHRACH H, BORKHARDT A, BOURQUIN JP, FRANKE A, KORBEL JO, STANULLA M, YASPO ML. Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. Nat Genet. 2015 Sep;47(9):1020-1029. doi: 10.1038/ng.3362. Epub 2015 Jul 27. PMID: 26214592; PMCID: PMC4603357.
- KRATZ CP, FRANKE L, PETERS H, KOHLSCHMIDT N, KAZMIERCZAK B, FINCKH U, BIER A, EICHHORN B, BLANK C, KRAUS C, KOHLHASE J, PAULI S, WILDHARDT G, KUTSCHE K, AUBER B, CHRISTMANN A, BACHMANN N, MITTER D, CREMER FW, MAYER K, DAUMER-HAAS C, NEVINNY-STICKEL-HINZPETER C, OEFFNER F, SCHLÜTER G, GENCIK M, ÜBERLACKER B, LISSEWSKI C, SCHANZE I, GREENE MH, SPIX C, ZENKER M. Cancer spectrum and frequency among children with Noonan, Costello, and cardio-facio-cutaneous syndromes. Br J Cancer. 2015 Apr 14;112(8):1392-7. doi: 10.1038/bjc.2015.75. Epub 2015 Mar 5. PMID: 25742478; PMCID: PMC4402457.
- KRATZ CP, EDELMAN DC, WANG Y, MELTZER PS, GREENE MH. Genetic and epigenetic analysis of monozygotic twins discordant for testicular cancer. Int J Mol Epidemiol Genet. 2014 Oct 22;5(3):135-9. PMID: 25379132; PMCID: PMC4214260.
- MUELLER CM, KORDE LA, MCMASTER ML, PETERS JA, BRATSLAVSKY G, WATKINS RJ, LING A, KRATZ CP, WULFSBERG EA, ROSENBERG PS, GREENE MH. Familial testicular germ cell tumor: no associated syndromic pattern identified. Hered Cancer Clin Pract. 2014 Feb 21;12(1):3. doi: 10.1186/1897-4287-12-3. PMID: 24559313; PMCID: PMC3937045.
- VASEN HF, GHORBANOGHLI Z, BOURDEAUT F, CABARET O, CARON O, DUVAL A, ENTZ-WERLE N, GOLDBERG Y, ILENCIKOVA D, KRATZ CP, LAVOINE N, LOEFFEN J, MENKO FH, MULERIS M, SEBILLE G, COLAS C, BURKHARDT B, BRUGIERES L, WIMMER K; EU-CONSORTIUM CARE FOR CMMR-D (C4CMMR-D). Guidelines for surveillance of individuals with constitutional mismatch repair-deficiency proposed by the European Consortium "Care for CMMR-D" (C4CMMR-D). J Med Genet. 2014 May;51(5):283-93. doi: 10.1136/jmedgenet-2013-102238. Epub 2014 Feb 20. PMID: 24556086.
- WIMMER K, KRATZ CP, VASEN HF, CARON O, COLAS C, ENTZ-WERLE N, GERDES AM, GOLDBERG Y, ILENCIKOVA D, MULERIS M, DUVAL A, LAVOINE N, RUIZ-PONTE C, SLAVC I, BURKHARDT B, BRUGIERES L; EU-CONSORTIUM CARE FOR CMMRD (C4CMMRD). Diagnostic criteria for constitutional mismatch repair deficiency syndrome: suggestions of the European consortium 'care for CMMRD' (C4CMMRD). J Med Genet. 2014 Jun;51(6):355-65. doi: 10.1136/jmedgenet-2014-102284. Epub 2014 Apr 15. PMID: 24737826.
- AZEVEDO MF, HORVATH A, BORNSTEIN ER, ALMEIDA MQ, XEKOUKI P, FAUCZ FR, GOURGARI E, NADELLA K, REMMERS EF, QUEZADO M, DE ALEXANDRE RB, KRATZ CP, NESTEROVA M, GREENE MH, STRATAKIS CA. Cyclic AMP and c-KIT signaling in familial testicular germ cell tumor predisposition. J Clin Endocrinol Metab. 2013 Aug;98(8):E1393-400. doi: 10.1210/jc.2012-2838. epub 2013 Jun 14. PMID: 23771924; PMCID: PMC3733859.
- CHUNG CC, KANETSKY PA, WANG Z, HILDEBRANDT MA, KOSTER R, SKOTHEIM RI, KRATZ CP, TURNBULL C, CORTESSIS VK, BAKKEN AC, BISHOP DT, COOK MB, ERICKSON RL, FOSSÅ SD, JACOBS KB, KORDE LA, KRAGGERUD SM, LOTHE RA, LOUD JT, RAHMAN N, SKINNER EC, THOMAS DC, WU X, YEAGER M, SCHUMACHER FR, GREENE MH, SCHWARTZ SM, MCGLYNN KA, CHANOCK SJ, NATHANSON KL. Meta-analysis identifies four new loci associated with testicular germ cell tumor. Nat Genet. 2013 Jun;45(6):680-5. doi: 10.1038/ng.2634. Epub 2013 May 12. PMID: 23666239; PMCID: PMC3723930.
- FARGO JH, KRATZ CP, GIRI N, SAVAGE SA, WONG C, BACKER K, ALTER BP, GLADER B. Erythrocyte adenosine deaminase: diagnostic value for Diamond-Blackfan anaemia. Br J Haematol. 2013 Feb;160(4):547-54. doi: 10.1111/bjh.12167. Epub 2012 Dec 17. PMID: 23252420; PMCID: PMC3609920.
- GERMESHAUSEN M, DEERBERG S, PETER Y, REIMER C, KRATZ CP, BALLMAIER M. The spectrum of ELANE mutations and their implications in severe congenital and cyclic neutropenia. Hum Mutat. 2013 Jun;34(6):905-14. doi: 10.1002/humu.22308. Epub 2013 Apr 2. PMID: 23463630.
- SCHULTZE-FLOREY RE, GRAF N, VORWERK P, KOSCIELNIAK E, SCHNEIDER DT, KRATZ CP. DICER1 syndrome: a new cancer syndrome. Clin Padiatr. 2013 May;225(3):177-8. doi: 10.1055/s-0033-1337976. epub 2013 Apr 26. PMID: 23625684.
- SCHUMACHER FR, WANG Z, SKOTHEIM RI, KOSTER R, CHUNG CC, HILDEBRANDT MA, KRATZ CP, BAKKEN AC, BISHOP DT, COOK MB, ERICKSON RL, FOSSÅ SD, GREENE MH, JACOBS KB, KANETSKY PA, KOLONEL LN, LOUD JT, KORDE LA, LE MARCHAND L, LEWINGER JP, LOTHE RA, PIKE MC, RAHMAN N, RUBERTONE MV, SCHWARTZ SM, SIEGMUND KD, SKINNER EC, TURNBULL C, VAN DEN BERG DJ, WU X, YEAGER M, NATHANSON KL, CHANOCK SJ, CORTESSIS VK, MCGLYNN KA. Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23. Hum Mol Genet. 2013 Jul 1;22(13):2748-53. doi: 10.1093/hmg/ddt109. Epub 2013 Mar 5. PMID: 23462292; PMCID: PMC3674801.
- JACOBS KB, YEAGER M, ZHOU W, WACHOLDER S, WANG Z, RODRIGUEZ-SANTIAGO B, HUTCHINSON A, DENG X, LIU C, HORNER MJ, CULLEN M, EPSTEIN CG, BURDETT L, DEAN MC, CHATTERJEE N, SAMPSON J, CHUNG CC, KOVAKS J, GAPSTUR SM, STEVENS VL, TERAS LT, GAUDET MM, ALBANES D, WEINSTEIN SJ, VIRTAMO J, TAYLOR PR, FREEDMAN ND, ABNET CC, GOLDSTEIN AM, HU N, YU K, YUAN JM, LIAO L, DING T, QIAO YL, GAO YT, KOH WP, XIANG YB, TANG ZZ, FAN JH, ALDRICH MC, AMOS C, BLOT WJ, BOCK CH, GILLANDERS EM, HARRIS CC, HAIMAN CA, HENDERSON BE, KOLONEL LN, LE MARCHAND L, MCNEILL LH, RYBICKI BA, SCHWARTZ AG, SIGNORELLO LB, SPITZ MR, WIENCKE JK, WRENSCH M, WU X, ZANETTI KA, ZIEGLER RG, FIGUEROA JD, GARCIA-CLOSAS M, MALATS N, MARENNE G, PROKUNINA-OLSSON L, BARIS D, SCHWENN M, JOHNSON A, LANDI MT, GOLDIN L, CONSONNI D, BERTAZZI PA, ROTUNNO M, RAJARAMAN P, ANDERSSON U, BEANE FREEMAN LE, BERG CD, BURING JE, BUTLER MA, CARREON T, FEYCHTING M, AHLBOM A, GAZIANO JM, GILES GG, HALLMANS G, HANKINSON SE, HARTGE P, HENRIKSSON R, INSKIP PD, JOHANSEN C, LANDGREN A, MCKEAN-COWDIN R, MICHAUD DS, MELIN BS, PETERS U, RUDER AM, SESSO HD, SEVERI G, SHU XO, VISVANATHAN K, WHITE E, WOLK A, ZELENIUCH-JACQUOTTE A, ZHENG W, SILVERMAN DT, KOGEVINAS M, GONZALEZ JR, VILLA O, LI D, DUELL EJ, RISCH HA, OLSON SH, KOOPERBERG C, WOLPIN BM, JIAO L, HASSAN M, WHEELER W, ARSLAN AA, BUENO-DE-MESQUITA HB, FUCHS CS, GALLINGER S, GROSS MD, HOLLY EA, KLEIN AP, LACROIX A, MANDELSON MT, PETERSEN G, BOUTRON-RUAULT MC, BRACCI PM, CANZIAN F, CHANG K, COTTERCHIO M, GIOVANNUCCI EL, GOGGINS M, HOFFMAN BOLTON JA, JENAB M, KHAW KT, KROGH V, KURTZ RC, MCWILLIAMS RR, MENDELSOHN JB, RABE KG, RIBOLI E, TJØNNELAND A, TOBIAS GS, TRICHOPOULOS D, ELENA JW, YU H, AMUNDADOTTIR L, STOLZENBERG-SOLOMON RZ, KRAFT P, SCHUMACHER F, STRAM D, SAVAGE SA, MIRABELLO L, ANDRULIS IL, WUNDER JS, PATIÑO GARCÍA A, SIERRASESÚMAGA L, BARKAUSKAS DA, GORLICK RG, PURDUE M, CHOW WH, MOORE LE, SCHWARTZ KL, DAVIS FG, HSING AW, BERNDT SI, BLACK A, WENTZENSEN N, BRINTON LA, LISSOWSKA J, PEPLONSKA B, MCGLYNN KA, COOK MB, GRAUBARD BI, KRATZ CP, GREENE MH, ERICKSON RL, HUNTER DJ, THOMAS G, HOOVER RN, REAL FX, FRAUMENI JF JR, CAPORASO NE, TUCKER M, ROTHMAN N, PÉREZ-JURADO LA, CHANOCK SJ. Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet. 2012 May 6;44(6):651-8. doi: 10.1038/ng.2270. PMID: 22561519; PMCID: PMC3372921.
- MIRABELLO L, KRATZ CP, SAVAGE SA, GREENE MH. Promoter methylation of candidate genes associated with familial testicular cancer. Int J Mol Epidemiol Genet. 2012;3(3):213-27. Epub 2012 Aug 31. PMID: 23050052; PMCID: PMC3459216.
- DÜHRSEN U, KRATZ CP, FLOTHO C, LAUENSTEIN T, BOMMER M, KÖNIG E, BRITTINGER G, HEIMPEL H. Long-term outcome of hemizygous and heterozygous carriers of a germline GATA1 (G208R) mutation. Ann Hematol. 2011 Mar;90(3):301-6. doi: 10.1007/s00277-010-1088-9. Epub 2010 Oct 5. PMID: 20922527; PMCID: PMC3115595.
- GREMER L, MERBITZ-ZAHRADNIK T, DVORSKY R, CIRSTEA IC, KRATZ CP, ZENKER M, WITTINGHOFER A, AHMADIAN MR. Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. Hum Mutat. 2011 Jan;32(1):33-43. doi: 10.1002/humu.21377. Epub 2010 Dec 9. PMID: 20949621; PMCID: PMC3117284.
- KRATZ CP, BRATSLAVSKY G, SHI J. The clinical utility of testicular cancer risk loci. Genome Med. 2011 Jan 21;3(1):1. doi: 10.1186/gm215. PMID: 21255381; PMCID: PMC3092086.
- KRATZ CP, GREENE MH, BRATSLAVSKY G, SHI J. A stratified genetic risk assessment for testicular cancer. Int J Androl. 2011 Aug;34(4 Pt 2):e98-102. doi: 10.1111/j.1365-2605.2011.01156.x. Epub 2011 May 12. PMID: 21564132; PMCID: PMC3145032.
- KRATZ CP, HAN SS, ROSENBERG PS, BERNDT SI, BURDETT L, YEAGER M, KORDE LA, MAI PL, PFEIFFER R, GREENE MH. Variants in or near KITLG, BAK1, DMRT1, and TERT-CLPTM1L predispose to familial testicular germ cell tumor. J Med Genet. 2011 Jul;48(7):473-6. doi: 10.1136/jmedgenet-2011-100001. Epub 2011 May 26. PMID: 21617256; PMCID: PMC3131696.
- KRATZ CP, RAPISUWON S, REED H, HASLE H, ROSENBERG PS. Cancer in Noonan, Costello, cardiofaciocutaneous and LEOPARD syndromes. Am J Med Genet C Semin Med Genet. 2011 May 15;157C(2):83-9. doi: 10.1002/ajmg.c.30300. Epub 2011 Apr 15. PMID: 21500339; PMCID: PMC3086183.
- ALLANSON JE, BOHRING A, DÖRR HG, DUFKE A, GILLESSEN-KAESBACH G, HORN D, KÖNIG R, KRATZ CP, KUTSCHE K, PAULI S, RASKIN S, RAUCH A, TURNER A, WIECZOREK D, ZENKER M. The face of Noonan syndrome: Does phenotype predict genotype. Am J Med Genet A. 2010 Aug;152A(8):1960-6. doi: 10.1002/ajmg.a.33518. PMID: 20602484; PMCID: PMC3115585.
- CHAO MM, TODD MA, KONTNY U, NEAS K, SULLIVAN MJ, HUNTER AG, PICKETTS DJ, KRATZ CP. T-cell acute lymphoblastic leukemia in association with Börjeson-Forssman-Lehmann syndrome due to a mutation in PHF6. Pediatr Blood Cancer. 2010 Oct;55(4):722-4. doi: 10.1002/pbc.22574. PMID: 20806366; PMCID: PMC2933084.
- CIRSTEA IC, KUTSCHE K, DVORSKY R, GREMER L, CARTA C, HORN D, ROBERTS AE, LEPRI F, MERBITZ-ZAHRADNIK T, KÖNIG R, KRATZ CP, PANTALEONI F, DENTICI ML, JOSHI VA, KUCHERLAPATI RS, MAZZANTI L, MUNDLOS S, PATTON MA, SILENGO MC, ROSSI C, ZAMPINO G, DIGILIO C, STUPPIA L, SEEMANOVA E, PENNACCHIO LA, GELB BD, DALLAPICCOLA B, WITTINGHOFER A, AHMADIAN MR, TARTAGLIA M, ZENKER M. A restricted spectrum of NRAS mutations causes Noonan syndrome. Nat Genet. 2010 Jan;42(1):27-9. doi: 10.1038/ng.497. Epub 2009 Dec 6. PMID: 19966803; PMCID: PMC3118669.
- GREENE MH, KRATZ CP, MAI PL, MUELLER C, PETERS JA, BRATSLAVSKY G, LING A, CHOYKE PM, PREMKUMAR A, BRACCI J, WATKINS RJ, MCMASTER ML, KORDE LA. Familial testicular germ cell tumors in adults: 2010 summary of genetic risk factors and clinical phenotype. Endocr Relat Cancer. 2010 Mar 8;17(2):R109-21. doi: 10.1677/ERC-09-0254. PMID: 20228134; PMCID: PMC3101798.
- KRATZ CP, MAI PL, GREENE MH. Familial testicular germ cell tumors. Best Pract Res Clin Endocrinol Metab. 2010 Jun;24(3):503-13. doi: 10.1016/j.beem.2010.01.005. PMID: 20833340; PMCID: PMC2939736.
- SAVOIA A, GERMESHAUSEN M, DE ROCCO D, HENSCHEL B, KRATZ CP, KUHLEN M, RATH B, STEUHL KP, WERMES C, BALLMAIER M. MYH9-related disease: Report on five German families and description of a novel mutation. Ann Hematol. 2010 Oct;89(10):1057-9. doi: 10.1007/s00277-010-0928-y. Epub 2010 Mar 10. PMID: 20221761.
- WIMMER K, KRATZ CP. Constitutional mismatch repair-deficiency syndrome. Haematologica. 2010 May;95(5):699-701. doi: 10.3324/haematol.2009.021626. PMID: 20442441; PMCID: PMC2864372.
- BOZTUG K, APPASWAMY G, ASHIKOV A, SCHÄFFER AA, SALZER U, DIESTELHORST J, GERMESHAUSEN M, BRANDES G, LEE-GOSSLER J, NOYAN F, GATZKE AK, MINKOV M, GREIL J, KRATZ C, PETROPOULOU T, PELLIER I, BELLANNÉ-CHANTELOT C, REZAEI N, MÖNKEMÖLLER K, IRANI-HAKIMEH N, BAKKER H, GERARDY-SCHAHN R, ZEIDLER C, GRIMBACHER B, WELTE K, KLEIN C. A syndrome with congenital neutropenia and mutations in G6PC3. N Engl J Med. 2009 Jan 1;360(1):32-43. doi: 10.1056/NEJMoa0805051. Erratum in: N Engl J Med. 2011 Apr 28;364(17):1682. PMID: 19118303; PMCID: PMC2778311.
- GERMESHAUSEN M, KRATZ CP, BALLMAIER M, WELTE K. RAS and CSF3R mutations in severe congenital neutropenia. Blood. 2009 Oct 15;114(16):3504-5. doi: 10.1182/blood-2009-07-232512. PMID: 19833857.
- KRATZ CP, HOLTER S, ETZLER J, LAUTEN M, POLLETT A, NIEMEYER CM, GALLINGER S, WIMMER K. Rhabdomyosarcoma in patients with constitutional mismatch-repair-deficiency syndrome. J Med Genet. 2009 Jun;46(6):418-20. doi: 10.1136/jmg.2008.064212. Epub 2009 Mar 16. PMID: 19293170.
- KRATZ CP, ZAMPINO G, KRIEK M, KANT SG, LEONI C, PANTALEONI F, OUDESLUYS-MURPHY AM, DI ROCCO C, KLOSKA SP, TARTAGLIA M, ZENKER M. Craniosynostosis in patients with Noonan syndrome caused by germline KRAS mutations. Am J Med Genet A. 2009 May;149A(5):1036-40. doi: 10.1002/ajmg.a.32786. PMID: 19396835.
- YANG Z, KONDO T, VOORHORST CS, NABINGER SC, NDONG L, YIN F, CHAN EM, YU M, WÜRSTLIN O, KRATZ CP, NIEMEYER CM, FLOTHO C, HASHINO E, CHAN RJ. Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutants. Mol Cell Biol. 2009 Aug;29(16):4376-93. doi: 10.1128/MCB.01330-08. Epub 2009 Jun 15. PMID: 19528235; PMCID: PMC2725726.
- ARCHAMBEAULT S, FLORES NJ, YOSHIMI A, KRATZ CP, REISING M, FISCHER A, NOELLKE P, LOCATELLI F, SEDLACEK P, FLOTHO C, ZECCA M, EMANUEL PD, CASTLEBERRY RP, NIEMEYER CM, BADER P, LOH ML. Development of an allele-specific minimal residual disease assay for patients with juvenile myelomonocytic leukemia. Blood. 2008 Feb 1;111(3):1124-7. doi: 10.1182/blood-2007-06-093302. epub 2007 Nov 13. PMID: 18000165; PMCID: PMC2214753.
- CHAN RJ, COOPER T, KRATZ CP, WEISS B, LOH ML. Juvenile myelomonocytic leukemia: a report from the 2nd International JMML Symposium. Leuk Res. 2009 Mar;33(3):355-62. doi: 10.1016/j.leukres.2008.08.022. Epub 2008 Oct 26. PMID: 18954903; PMCID: PMC2692866.
- ETZLER J, PEYRL A, ZATKOVA A, SCHILDHAUS HU, FICEK A, MERKELBACH-BRUSE S, KRATZ CP, ATTARBASCHI A, HAINFELLNER JA, YAO S, MESSIAEN L, SLAVC I, WIMMER K. RNA-based mutation analysis identifies an unusual MSH6 splicing defect and circumvents PMS2 pseudogene interference. Hum Mutat. 2008 Feb;29(2):299-305. doi: 10.1002/humu.20657. PMID: 18030674.
- FLOTHO C, KRATZ CP, BERGSTRÄSSER E, HASLE H, STARÝ J, TREBO M, VAN DEN HEUVEL-EIBRINK MM, WÓJCIK D, ZECCA M, LOCATELLI F, NIEMEYER CM; EUROPEAN WORKING GROUP OF MYELODYSPLASTIC SYNDROMES IN CHILDHOOD. Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations. Blood. 2008 Jan 15;111(2):966-7; author reply 967-8. doi: 10.1182/blood-2007-09-111831. PMID: 18182584.
- KAROW A, WALLER C, REIMANN C, NIEMEYER CM, KRATZ CP. JAK2 mutations other than V617F: a novel mutation and mini review. Leuk Res. 2008 Feb;32(2):365-6. doi: 10.1016/j.leukres.2007.02.018. Epub 2007 Apr 26. PMID: 17466371.
- KRATZ CP, NIEMEYER CM, KAROW A, VOLZ-FLECKENSTEIN M, SCHMITT-GRÄFF A, STRAHM B. Congenital transfusion-dependent anemia and thrombocytopenia with myelodysplasia due to a recurrent GATA1(G208R) germline mutation. Leukemia. 2008 Feb;22(2):432-4. doi: 10.1038/sj.leu.2404904. Epub 2007 Aug 23. PMID: 17713552.
- LAUX D, KRATZ C, SAUERBREY A. Common acute lymphoblastic leukemia in a girl with genetically confirmed LEOPARD syndrome. J Pediatr Hematol Oncol. 2008 Aug;30(8):602-4. doi: 10.1097/MPH.0b013e31817588fb. PMID: 18799937.
- NIEMEYER CM, KRATZ CP. Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia: molecular classification and treatment options. Br J Haematol. 2008 Mar;140(6):610-24. doi: 10.1111/j.1365-2141.2007.06958.x. PMID: 18302710.
- PÉRON S, METIN A, GARDÈS P, ALYANAKIAN MA, SHERIDAN E, KRATZ CP, FISCHER A, DURANDY A. Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination. J Exp Med. 2008 Oct 27;205(11):2465-72. doi: 10.1084/jem.20080789. Epub 2008 Sep 29. PMID: 18824584; PMCID: PMC2571921.
- PFISTER S, JANZARIK WG, REMKE M, ERNST A, WERFT W, BECKER N, TOEDT G, WITTMANN A, KRATZ C, OLBRICH H, AHMADI R, THIEME B, JOOS S, RADLWIMMER B, KULOZIK A, PIETSCH T, HEROLD-MENDE C, GNEKOW A, REIFENBERGER G, KORSHUNOV A, SCHEURLEN W, OMRAN H, LICHTER P. BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. J Clin Invest. 2008 May;118(5):1739-49. doi: 10.1172/JCI33656. PMID: 18398503; PMCID: PMC2289793.
- SCHUBBERT S, BOLLAG G, LYUBYNSKA N, NGUYEN H, KRATZ CP, ZENKER M, NIEMEYER CM, MOLVEN A, SHANNON K. Biochemical and functional characterization of germ line KRAS mutations. Mol Cell Biol. 2007 Nov;27(22):7765-70. doi: 10.1128/MCB.00965-07. Epub 2007 Sep 17. PMID: 17875937; PMCID: PMC2169154.
- DE VRIES AC, STAM RW, KRATZ CP, ZENKER M, NIEMEYER CM, VAN DEN HEUVEL-EIBRINK MM; EUROPEAN WORKING GROUP ON CHILDHOOD MDS (EWOG-MDS). Mutation analysis of the BRAF oncogene in juvenile myelomonocytic leukemia. Haematologica. 2007 Nov;92(11):1574-5. doi: 10.3324/haematol.11493. PMID: 18024410.
- DE VRIES AC, STAM RW, SCHNEIDER P, NIEMEYER CM, VAN WERING ER, HAAS OA, KRATZ CP, DEN BOER ML, PIETERS R, VAN DEN HEUVEL-EIBRINK MM. Role of mutation independent constitutive activation of FLT3 in juvenile myelomonocytic leukemia. Haematologica. 2007 Nov;92(11):1557-60. doi: 10.3324/haematol.11201. PMID: 18024405.
- EL-MONEIM AA, KRATZ CP, BÖLL S, RISTER M, PAHL HL, NIEMEYER CM. Essential versus reactive thrombocythemia in children: retrospective analyses of 12 cases. Pediatr Blood Cancer. 2007 Jul;49(1):52-5. doi: 10.1002/pbc.21128. PMID: 17171694.
- FLOTHO C, KRATZ C, NIEMEYER CM. Targeting RAS signaling pathways in juvenile myelomonocytic leukemia. Curr Drug Targets. 2007 Jun;8(6):715-25. doi: 10.2174/138945007780830773. PMID: 17584027.
- FLOTHO C, KRATZ CP, NIEMEYER CM. How a rare pediatric neoplasia can give important insights into biological concepts: a perspective on juvenile myelomonocytic leukemia. Haematologica. 2007 Nov;92(11):1441-6. doi: 10.3324/haematol.11280. PMID: 18024390.
- FLOTHO C, STEINEMANN D, MULLIGHAN CG, NEALE G, MAYER K, KRATZ CP, SCHLEGELBERGER B, DOWNING JR, NIEMEYER CM. Genome-wide single-nucleotide polymorphism analysis in juvenile myelomonocytic leukemia identifies uniparental disomy surrounding the NF1 locus in cases associated with neurofibromatosis but not in cases with mutant RAS or PTPN11. Oncogene. 2007 Aug 23;26(39):5816-21. doi: 10.1038/sj.onc.1210361. Epub 2007 Mar 12. PMID: 17353900.
- HINDERSIN S, NIEMEYER CM, GERMING U, GÖBEL U, KRATZ CP. Mutation analysis of CUTL1 in childhood myeloid neoplasias with monosomy 7. Leuk Res. 2007 Sep;31(9):1323-4. doi: 10.1016/j.leukres.2006.10.021. Epub 2006 Nov 30. PMID: 17140660.
- JANZARIK WG, KRATZ CP, LOGES NT, OLBRICH H, KLEIN C, SCHÄFER T, SCHEURLEN W, ROGGENDORF W, WEILLER C, NIEMEYER C, KORINTHENBERG R, PFISTER S, OMRAN H. Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma. Neuropediatrics. 2007 Apr;38(2):61-3. doi: 10.1055/s-2007-984451. PMID: 17712732.
- KAROW A, STEINEMANN D, GÖHRING G, HASLE H, GREINER J, HARILA-SAARI A, FLOTHO C, ZENKER M, SCHLEGELBERGER B, NIEMEYER CM, KRATZ CP. Clonal duplication of a germline PTPN11 mutation due to acquired uniparental disomy in acute lymphoblastic leukemia blasts from a patient with Noonan syndrome. Leukemia. 2007 Jun;21(6):1303-5. doi: 10.1038/sj.leu.2404651. Epub 2007 Mar 15. PMID: 17361219.
- KRATZ CP, NIEMEYER CM, JÜTTNER E, KARTAL M, WENINGER A, SCHMITT-GRAEFF A, KONTNY U, LAUTEN M, UTZOLINO S, RÄDECKE J, FONATSCH C, WIMMER K. Childhood T-cell non-Hodgkin's lymphoma, colorectal carcinoma and brain tumor in association with café-au-lait spots caused by a novel homozygous PMS2 mutation. Leukemia. 2008 May;22(5):1078-80. doi: 10.1038/sj.leu.2405008. Epub 2007 Nov 15. PMID: 18007577.
- KRATZ CP, NIEMEYER CM, THOMAS C, BAUHUBER S, MATEJAS V, BERGSTRÄSSER E, FLOTHO C, FLORES NJ, HAAS O, HASLE H, VAN DEN HEUVEL-EIBRINK MM, KUCHERLAPATI RS, LANG P, ROBERTS AE, STARÝ J, STRAHM B, SWANSON KD, TREBO M, ZECCA M, NEEL B, LOCATELLI F, LOH ML, ZENKER M. Mutation analysis of Son of Sevenless in juvenile myelomonocytic leukemia. Leukemia. 2007 May;21(5):1108-9. doi: 10.1038/sj.leu.2404620. Epub 2007 Feb 22. PMID: 17315019.
- KRATZ CP, NIEMEYER CM, ZENKER M. An unexpected new role of mutant Ras: perturbation of human embryonic development. J Mol Med (Berl). 2007 Mar;85(3):227-35. doi: 10.1007/s00109-006-0135-4. Epub 2007 Jan 9. PMID: 17211612; PMCID: PMC1820751.
- KRATZ CP, STEINEMANN D, NIEMEYER CM, SCHLEGELBERGER B, KOSCIELNIAK E, KONTNY U, ZENKER M. Uniparental disomy at chromosome 11p15.5 followed by HRAS mutations in embryonal rhabdomyosarcoma: lessons from Costello syndrome. Hum Mol Genet. 2007 Feb 15;16(4):374-9. doi: 10.1093/hmg/ddl458. Epub 2006 Dec 12. Erratum in: Hum Mol Genet. 2007 Nov 15;16(22):2781. PMID: 17164262.
- PEIXOTO NC, KRATZ CP, ROZA T, MORSCH VM, PEREIRA ME. Effects of HgCl2 on porphobilinogen synthase (E.C. 4.2.1.24) activity and on mercury levels in rats exposed during different precocious periods of postnatal life. Cell Biol Int. 2007 Sep;31(9):1057-62. doi: 10.1016/j.cellbi.2007.03.026. Epub 2007 Mar 28. PMID: 17490898.
- VAN DER BURGT I, KUPSKY W, STASSOU S, NADROO A, BARROSO C, DIEM A, KRATZ CP, DVORSKY R, AHMADIAN MR, ZENKER M. Myopathy caused by HRAS germline mutations: implications for disturbed myogenic differentiation in the presence of constitutive HRas activation. J Med Genet. 2007 Jul;44(7):459-62. doi: 10.1136/jmg.2007.049270. Epub 2007 Apr 5. PMID: 17412879; PMCID: PMC2598013.
- YETGIN S, AYTAC S, KALKANOGLU S, COSKUN T, ORTMANN C, KRATZ C, NIEMEYER C. Biotinidase deficiency and juvenile myelomonocytic leukemia in a Turkish infant of consanguineous parents. Pediatr Hematol Oncol. 2007 Sep;24(6):453-5. doi: 10.1080/08880010701451293. PMID: 17710663.
- ZENKER M, HORN D, WIECZOREK D, ALLANSON J, PAULI S, VAN DER BURGT I, DOERR HG, GASPAR H, HOFBECK M, GILLESSEN-KAESBACH G, KOCH A, MEINECKE P, MUNDLOS S, NOWKA A, RAUCH A, REIF S, VON SCHNAKENBURG C, SEIDEL H, WEHNER LE, ZWEIER C, BAUHUBER S, MATEJAS V, KRATZ CP, THOMAS C, KUTSCHE K. SOS1 is the second most common Noonan gene but plays no major role in cardio-facio-cutaneous syndrome. J Med Genet. 2007 Oct;44(10):651-6. doi: 10.1136/jmg.2007.051276. Epub 2007 Jun 23. PMID: 17586837; PMCID: PMC2597961.
- ZENKER M, LEHMANN K, SCHULZ AL, BARTH H, HANSMANN D, KOENIG R, KORINTHENBERG R, KREISS-NACHTSHEIM M, MEINECKE P, MORLOT S, MUNDLOS S, QUANTE AS, RASKIN S, SCHNABEL D, WEHNER LE, KRATZ CP, HORN D, KUTSCHE K. Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations. J Med Genet. 2007 Feb;44(2):131-5. doi: 10.1136/jmg.2006.046300. Epub 2006 Oct 20. PMID: 17056636; PMCID: PMC2598066.
- KRATZ CP, BÖLL S, KONTNY U, SCHRAPPE M, NIEMEYER CM, STANULLA M. Mutational screen reveals a novel JAK2 mutation, L611S, in a child with acute lymphoblastic leukemia. Leukemia. 2006 Feb;20(2):381-3. doi: 10.1038/sj.leu.2404060. PMID: 16341038.
- KRATZ CP, NATHRATH M, FREISINGER P, DRESSEL P, ASSMUSS HP, KLEIN C, YOSHIMI A, BURDACH S, NIEMEYER CM. Lethal proliferation of erythroid precursors in a neonate with a germline PTPN11 mutation. Eur J Pediatr. 2006 Mar;165(3):182-5. doi: 10.1007/s00431-005-0031-x. Epub 2005 Dec 21. PMID: 16369799.
- KRATZ CP, SCHUBBERT S, BOLLAG G, NIEMEYER CM, SHANNON KM, ZENKER M. Germline mutations in components of the Ras signaling pathway in Noonan syndrome and related disorders. Cell Cycle. 2006 Aug;5(15):1607-11. doi: 10.4161/cc.5.15.3128. Epub 2006 Aug 1. PMID: 16921267.
- ORTMANN CA, NIEMEYER CM, WAWER A, EBELL W, BAUMANN I, KRATZ CP. TERC mutations in children with refractory cytopenia. Haematologica. 2006 May;91(5):707-8. PMID: 16670076.
- REIMANN C, AROLA M, BIERINGS M, KAROW A, VAN DEN HEUVEL-EIBRINK MM, HASLE H, NIEMEYER CM, KRATZ CP. A novel somatic K-Ras mutation in juvenile myelomonocytic leukemia. Leukemia. 2006 Sep;20(9):1637-8. doi: 10.1038/sj.leu.2404303. epub 2006 Jul 6. PMID: 16826224.
- SCHUBBERT S, ZENKER M, ROWE SL, BÖLL S, KLEIN C, BOLLAG G, VAN DER BURGT I, MUSANTE L, KALSCHEUER V, WEHNER LE, NGUYEN H, WEST B, ZHANG KY, SISTERMANS E, RAUCH A, NIEMEYER CM, SHANNON K, KRATZ CP. Germline KRAS mutations cause Noonan syndrome. Nat Genet. 2006 Mar;38(3):331-6. doi: 10.1038/ng1748. Epub 2006 Feb 12. Erratum in: Nat Genet. 2006 May;38(5):598. PMID: 16474405.
- CURTISS NP, BONIFAS JM, LAUCHLE JO, BALKMAN JD, KRATZ CP, EMERLING BM, GREEN ED, LE BEAU MM, SHANNON KM. Isolation and analysis of candidate myeloid tumor suppressor genes from a commonly deleted segment of 7q22. Genomics. 2005 May;85(5):600-7. doi: 10.1016/j.ygeno.2005.01.013. PMID: 15820312.
- GERMESHAUSEN M, SCHULZE H, KRATZ C, WILKENS L, REPP R, SHANNON K, WELTE K, BALLMAIER M. An acquired G-CSF receptor mutation results in increased proliferation of CMML cells from a patient with severe congenital neutropenia. Leukemia. 2005 Apr;19(4):611-7. doi: 10.1038/sj.leu.2403663. PMID: 15729385.
- KRATZ CP, NIEMEYER CM, CASTLEBERRY RP, CETIN M, BERGSTRÄSSER E, EMANUEL PD, HASLE H, KARDOS G, KLEIN C, KOJIMA S, STARY J, TREBO M, ZECCA M, GELB BD, TARTAGLIA M, LOH ML. The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease. Blood. 2005 Sep 15;106(6):2183-5. doi: 10.1182/blood-2005-02-0531. Epub 2005 May 31. PMID: 15928039; PMCID: PMC1895140.
- KRATZ CP, NIEMEYER CM. Juvenile myelomonocytic leukemia. Hematology. 2005;10 Suppl 1:100-3. doi: 10.1080/10245330512331390078. PMID: 16188648.
- KRATZ CP, ROGGE T, KOPP M, BAUMANN I, NIEMEYER CM. Myelodysplastic features in an infant with cystic fibrosis presenting with anaemia, oedema and failure to thrive. Eur J Pediatr. 2005 Jan;164(1):56-7. doi: 10.1007/s00431-004-1548-0. Epub 2004 Oct 23. PMID: 15517378.
- NIEMEYER CM, KRATZ CP, HASLE H. Pediatric myelodysplastic syndromes. Curr Treat Options Oncol. 2005 May;6(3):209-14. doi: 10.1007/s11864-005-0004-3. PMID: 15869732.
- NIEMEYER CM, KRATZ CP. Is granulocyte colony-stimulating factor therapy a risk factor for myelodysplasia/leukemia in patients with congenital neutropenia? Haematologica. 2005 Jan;90(1):2-3. PMID: 15644298.
- KRATZ CP, ABD EL-MONHEIM A, MANKE EM, RISTER M, ROGGE T, NIEMEYER CM. Retrospective analysis of the clinical course of 12 children given the diagnosis essential thrombocythemia]. Clin Padiatr. 2004 Nov-Dec;216(6):349-55. doi: 10.1055/s-2004-832356. PMID: 15565550.
- KRATZ CP, ANTONIETTI L, SHANNON KM, DOLE MG, FRIEBERT SE. Acute myeloid leukemia associated with t(8;21) or trisomy 8 in children with neurofibromatosis, type 1. J Pediatr Hematol Oncol. 2003 Apr;25(4):343. doi: 10.1097/00043426-200304000-00018. PMID: 12679655.
- KRATZ CP, NIEHUES T, LYDING S, HEUSCH A, JANSSEN G, GÖBEL U. Evans syndrome in a patient with chromosome 22q11.2 deletion syndrome: a case report. Pediatr Hematol Oncol. 2003 Mar;20(2):167-72. doi: 10.1080/0880010390158685. PMID: 12554529.
- KRATZ CP, SCHWEIGER B, KEMPERDICK H, GÖBEL U. Childhood multifocal skeletal non-Hodgkin lymphoma is a differential diagnosis of battered child syndrome. Pediatr Hematol Oncol. 2003 Dec;20(8):575-7. PMID: 14578025.
- NIEMEYER CM, KRATZ C. Juvenile myelomonocytic leukemia. Curr Oncol Rep. 2003 Nov;5(6):510-5. doi: 10.1007/s11912-003-0013-y. PMID: 14521811.
- NIEMEYER CM, KRATZ C. Juvenile myelomonocytic leukemia. Curr Treat Options Oncol. 2003 Jun;4(3):203-10. doi: 10.1007/s11864-003-0021-z. PMID: 12718797.
- EMERLING BM, BONIFAS J, KRATZ CP, DONOVAN S, TAYLOR BR, GREEN ED, LE BEAU MM, SHANNON KM. MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia. Oncogene. 2002 Jul 18;21(31):4849-54. doi: 10.1038/sj.onc.1205615. PMID: 12101424.
- KRATZ CP, EMERLING BM, BONIFAS J, WANG W, GREEN ED, LE BEAU MM, SHANNON KM. Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor. Blood. 2002 Jan 1;99(1):372-4. doi: 10.1182/blood.v99.1.372. PMID: 11756194.
- KRATZ CP, EMERLING BM, DONOVAN S, LAIG-WEBSTER M, TAYLOR BR, THOMPSON P, JENSEN S, BANERJEE A, BONIFAS J, MAKALOWSKI W, GREEN ED, LE BEAU MM, SHANNON KM. Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies. Genomics. 2001 Oct;77(3):171-80. doi: 10.1006/geno.2001.6636. PMID: 11597142.
- KRATZ C, MAUZ-KÖRHOLZ C, KRUCK H, KÖRHOLZ D, GÖBEL U. Detection of antiphospholipid antibodies in children and adolescents. Pediatr Hematol Oncol. 1998 Jul-Aug;15(4):325-32. doi: 10.3109/08880019809014016. PMID: 9658433.
- GRÖBNER SN, WORST BC, WEISCHENFELDT J, BUCHHALTER I, KLEINHEINZ K, RUDNEVA VA, JOHANN PD, BALASUBRAMANIAN GP, SEGURA-WANG M, BRABETZ S, BENDER S, HUTTER B, STURM D, PFAFF E, HÜBSCHMANN D, ZIPPRICH G, HEINOLD M, EILS J, LAWERENZ C, ERKEK S, LAMBO S, WASZAK S, BLATTMANN C, BORKHARDT A, KUHLEN M, EGGERT A, FULDA S, GESSLER M, WEGERT J, KAPPLER R, BAUMHOER D, BURDACH S, KIRSCHNER-SCHWABE R, KONTNY U, KULOZIK AE, LOHMANN D, HETTMER S, ECKERT C, BIELACK S, NATHRATH M, NIEMEYER C, RICHTER GH, SCHULTE J, SIEBERT R, WESTERMANN F, MOLENAAR JJ, VASSAL G, WITT H; ICGC PEDBRAIN-SEQ PROJECT; ICGC MMML-SEQ PROJECT, BURKHARDT B, KRATZ CP, WITT O, VAN TILBURG CM, KRAMM CM, FLEISCHHACK G, DIRKSEN U, RUTKOWSKI S, FRÜHWALD M, VON HOFF K, WOLF S, KLINGEBIEL T, KOSCIELNIAK E, LANDGRAF P, KOSTER J, RESNICK AC, ZHANG J, LIU Y, ZHOU X, WAANDERS AJ, ZWIJNENBURG DA, RAMAN P, BRORS B, WEBER UD, NORTHCOTT PA, PAJTLER KW, KOOL M, PIRO RM, KORBEL JO, SCHLESNER M, EILS R, JONES DTW, LICHTER P, CHAVEZ L, ZAPATKA M, PFISTER SM. The landscape of genomic alterations across childhood cancers. Nature. 2018 Mar 15;555(7696):321-327. doi: 10.1038/nature25480. Epub 2018 Feb 28. Erratum in: Nature. 2018 Jul;559(7714):E10. PMID: 29489754.
- RIPPERGER T, BIELACK SS, BORKHARDT A, BRECHT IB, BURKHARDT B, CALAMINUS G, DEBATIN KM, DEUBZER H, DIRKSEN U, ECKERT C, EGGERT A, ERLACHER M, FLEISCHHACK G, FRÜHWALD MC, GNEKOW A, GOEHRING G, GRAF N, HANENBERG H, HAUER J, HERO B, HETTMER S, VON HOFF K, HORSTMANN M, HOYER J, ILLIG T, KAATSCH P, KAPPLER R, KERL K, KLINGEBIEL T, KONTNY U, KORDES U, KÖRHOLZ D, KOSCIELNIAK E, KRAMM CM, KUHLEN M, KULOZIK AE, LAMOTTKE B, LEUSCHNER I, LOHMANN DR, MEINHARDT A, METZLER M, MEYER LH, MOSER O, NATHRATH M, NIEMEYER CM, NUSTEDE R, PAJTLER KW, PARET C, RASCHE M, REINHARDT D, RIESS O, RUSSO A, RUTKOWSKI S, SCHLEGELBERGER B, SCHNEIDER D, SCHNEPPENHEIM R, SCHRAPPE M, SCHROEDER C, VON SCHWEINITZ D, SIMON T, SPARBER-SAUER M, SPIX C, STANULLA M, STEINEMANN D, STRAHM B, TEMMING P, THOMAY K, VON BUEREN AO, VORWERK P, WITT O, WLODARSKI M, WÖSSMANN W, ZENKER M, ZIMMERMANN S, PFISTER SM, KRATZ CP. Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology. Am J Med Genet A. 2017 Apr;173(4):1017-1037. doi: 10.1002/ajmg.a.38142. Epub 2017 Feb 7. PMID: 28168833.
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Close cooperation with the treatment partners:
Clinical Department of Neurology (MHH) Clinical Department for Radiotherapy (MHH) Institute of Diagnostic and Interventional Neuroradiology (MHH) Institute of Pathology, specializing in Neuropathology (MHH) Clinical Department of Pediatric Hematology and Oncology (MHH) Clinical Department of Paediatric Kidney, Liver and Metabolic Diseases (MHH) Institute of Human Genetics, Chair of Neurooncogenetics (MHH)
Certified quality
The Neurooncology Center meets the quality criteria defined by the German Cancer Society and receives the award "Neurooncology Center with Recommendation of the German Cancer Society e.V."
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