Many cancers are caused by external influences such as radiation or nicotine consumption. They also generally affect older patients. However, around 5-10% of all people with cancer have a hereditary cancer risk. This so-called cancer predisposition is actually the most common known cause of malignant diseases in children and adolescents.
At Hannover Medical School, the Institute of Human Genetics (Director: Prof. Dr. med. Brigitte Schlegelberger) and the Clinical Department of Pediatric Hematology and Oncology (Director: Prof. Dr. med. Christian Kratz) focus on advising and caring for people with cancer predisposition syndromes.
Through close cooperation between the two centers and with various other Clinical Departments and Institutes of the MHH, modern examination methods and special consultation hours, we want to provide holistic care and be a competent point of contact for those affected, from diagnosis to consultation and therapy.
Competencies of the specialist center
- Human genetic diagnostics using the latest methods
- Genetic counseling
- Consultation hours for children with cancer predisposition syndromes and long-term care
- Clinical, laboratory and radiological diagnostics for children with cancer predisposition syndromes
- Treatment of children with cancer predisposition syndromes
- Cancer predisposition registry
Contact details
Centre for Rare Diseases
B-Center for Cancer Predisposition
Hannover Medical School
Carl-Neuberg-Str. 1
30625 Hannover
The following links will provide you with further information and help on the subject of cancer predisposition:
There are already numerous self-help groups for the individual rare genetic syndromes and the various cancer predisposition syndromes. You can find more information under the following links:
- To the website "Portal for rare diseases and orphan drugs" Orphanet
- To the website "Care atlas for people with rare diseases" SE-Atlas
- To the website "Alliance of Chronic Rare Diseases" ACHSE e.V.
Please refer to the list below for an overview of ZSE specialist centers participating in registries:
Clinical trials with the participation of ZSE-B centers:
You can download the current publications of this ZSE-B center as PDF files under the following link: