Small animal imaging center Non-invasive and in vivo imaging methods are of particular importance for the longitudinal investigation of animal models for human diseases. These modalities can be divided [...] multimodal platform for studies on small animal models. Technical equipment Bruker 7T Pharmascan 70/16 (magnetic resonance tomograph), µCT Siemens Inveon: (small animal computer tomograph), FMT Perkin Elmer [...] tomograph), IVIS SpectrumCT (bioluminescence tomograph) Ultrasound Visualsonics Vevo 2100 (small animal ultrasound), Special workstations for the evaluation of MRI, µCT and FMT data are available. Your

Veterinary care The veterinary care of the animals used in animal experiments or intended for animal experiments is provided by the veterinarians and employees of the individual working groups. If required [...] contact persons Dr. Silke Glage Inga Brüsch, PhD Dr. Regina Rumpel Lena Brix Institute for Laboratory Animal Science Hannover Medical School Carl-Neuberg-Straße1 +49 511 532-3939 +49 511 532-3710

remarkable insofar as demands for equal rights, claims or evaluations for humans and animals have long been established in animal ethics, which are obviously gaining plausibility for many people. There are currently [...] discourse on the end of life of humans and pets and consequences for the relationship between medical and animal ethics Dying a dog's death? Converging and diverging ethical discourses in human and veterinary medicine [...] end of life care for humans and pets and some consequences for the relations between medical and animal ethics Funding: German Research Foundation (DFG) Duration: January 2019 to December 2021 Team Pu

gnotobiology laboratory, germ-free (axenic) animals or animals associated with a defined flora (gnotobiotic) are generated and kept (mouse, rat). The animals are kept in isolators, which are operated as [...] y laboratory) Association experiments with various pathogens Back to the homepage of the Central Animal Laboratory

primarily investigated using large animal models such as pigs or sheep. However, sophisticated surgical research is only possible if the perioperative care of the animals in the context of anesthesia, intensive [...] the depth of anesthesia (refinement in animal experiments) Collaborations and research networks TBA TBA Publications TBA Back to the homepage of the Central Animal Laboratory

Central Animal Laboratory and focuses on the following areas: genetic diagnostics, health diagnostics, reproductive biology, experimental surgery and the care of laboratory animals in the Central Animal Laboratory [...] vocational school. The BFJ can be credited towards the training period. Your contact person is: Central Animal Laboratory - OE 8600 PD Dr. Dirk Wedekind Tel: +49 511 532-3715 Dirk Wedekind

current scientific interest. This makes sense for both animal welfare and economic reasons. Embryos or sperm can be shipped worldwide instead of live animals. The following cells can be cryopreserved for stem [...] function of the transplanted ovary is restored and the recipient animal can be used for breeding. Back to the homepage of the Central Animal Laboratory

Kunzmann, P. (2020). Philosophy of a "Good Death" in Small Animals and Consequences for Euthanasia in Animal Law and Veterinary Practice. Animals , 10(1), 124. [...] discourse on the end of life of humans and pets and consequences for the relationship between medical and animal ethics Publications Selter, F., Persson, K., Neitzke, G. (2022). Moral distress and euthanasia: what

disease (IBD) in animal models, infection models and gnotobiology as well as experimental animal projects . In the latter, the focus is particularly on the influence of murine pathogens on animal models and [...] assessment of laboratory animals. In our experimental work on CED, we are interested in how genetic and microbial factors influence inflammatory reactions and tolerance development in animal models. The genetic [...] such as bioluminescence or MRI, work with infection models and work on germ-free and gnotobiotic animals. (Prof. André Bleich , head of the working group) Collaborations and research networks DFG-SFB621

Research report 2015 Cover picture: The cover image/animation of the 2015 research report shows an animation with the in vitro uptake of 30-100 nM sized exosomes in cardiomyocytes. Exosomes are a type [...] was performed. In the animation, cardiomyocytes are stained green (membrane staining), fibroblast exosomes are stained red and the cell nuclei are stained blue (DAPI). The animation was provided by Prof [...] microRNAs (class of non-coding RNAs) can trigger pathological size growth in cardiomyocytes. In the animation shown here, exosomes were isolated from a fibroblast culture via several centrifugation steps,