molecular biology, histology, immunohistology, immunohistochemistry and cell biology, as well as in animal models. This is made possible by the latest equipment, such as a flow cytometer equipped with four [...] and a digital 4K microscope are used to analyze the preparations. Our laboratory also has its own animal operating room for mice and rats with an isoflurane anesthesia and suction unit. You can find more
of the area is complemented by additional rooms for data processing, project meetings, storage and animal husbandry. The supply of radiopharmaceuticals for various examinations, as well as quality control [...] Protection/Medical Physics Unit . The department is operated in close coordination with the central animal laboratory of the MHH . A permanent staff (laboratory manager, technical assistants, laboratory
point for a joint scientific project or a cooperation within the framework of a clinical study or an animal experiment. Please note Due to staff shortages, there are currently only a limited number of consultation [...] than the day before the consultation appointment. If you already have a study protocol (draft) or an animal experiment application, please also send us these documents at least one day before the consultation
Medical Center Utrecht these tissues are transplanted for preclinical testing into damaged hearts in animal models. Monitoring the (electro-) physiological integration of the transplanted cells is another [...] Endothelial cells (ECs) and pericytes (PCs) differentiation WP 7 Mesenchymal Stem Cells (MSC) WP 8 Large animal model, in vivo cell monitoring and function WP 9 Regulatory compliance and exploitation WP 10 Management
Research report 2018 The animation or cover image shows hybrid imaging of the heart with positron emission tomography (PET) / X-ray computed tomography (CT) in a patient 5 days after an acute myocardial [...] However, we would like to take the opportunity here to explicitly present a representative project. Animation Copyright: Bengel, Clinical Department of Nuclear Medicine, MHH Imprint Publisher: President of
Project presentation 2019 The animation or cover image shows the innovative "prime editing" process for precisely correcting DNA changes in cells. In this process, the CRISPR/Cas9 system is guided precisely [...] aim of the work is also to investigate future forms of application directly in the organism. The animation was created by Prof. Dr. med. Tobias Cantz (Translational Hepatology and Stem Cell Biology working
Our group investigates the role of CD8 T cells in acute and chronic infection models as well as in animal models of gastrointestinal tumors. A particular research focus of our group is hepatocellular carcinoma [...] pathogen-specific T cells. The focus of our oncological investigations is the establishment of practical animal models for hepatocellular carcinoma and other gastrointestinal tumors (e.g. pancreas) and the development
consider your request. You will hear from us as soon as possible. Kind regards, the team of the Central Animal Laboratory
s are required. These methods should allow for the tracking of the cells in not only preclinical animal models but later also in patients. In the present study, the research team led by Professor Dr. Ulrich [...] this might allow for the monitoring of survival and distribution of transplanted stem cells in both animal model and patients. In fact, using modern clinical imaging methods, these modified iPS cells could
new recombinant coagulation factor concentrates, which are produced completely free of human and animal proteins. In addition, projects on patient-reported outcomes (PROs) and quality of life are being [...] analysis), signal transduction, translational epigenetics, immunophenotyping and functional analysis in animal models). - The research group 5659 "TARGET-MPN" (spokesperson: Prof. Dr. F. Heidel) and the Emmy