German Tumour Centre, he moved in 1987 to the Institute of Genetics at the Faculty of Natural Sciences at the University of Bonn, where he habilitated in genetics and immunology in 1993. In the same year, [...] their home institutes. In 2018, Prof. Abken moved to the University of Regensburg, where he holds the Chair of Gene Immunotherapy, has played a major role in establishing the Leibniz Institute for Immunotherapy [...] associate at the LOEWE centre Frankfurt Cancer Institute. Since 2021, the 39-year-old has headed his own research group at the Pharmacological Institute of the Department of Medicine at Philipps University
in use act by interfering with the cell coat assembly. The parasites Leishmania , responsible for human diseases collectively called leishmaniases and the opportunistic fungus Aspergillus fumigatus , the [...] Our projects aim at: Identifying and characterizing new glycosylation pathways (ideally absent in human) Analyzing their importance for the pathogen survival, growth or virulence (in mice models) to identify [...] development of lead compounds (in collaboration with specialist). Methods commonly used include genetic manipulation of pathogens (e.g. gene disruption, conditional regulation of gene expression, protein
Neurology Institute of Biostatistics Institute of Clinical Pharmacology Department of Nuclear Medicine With external institutions - Germany-wide Section Biostatistics at Paul-Ehrlich-Institute Department [...] Unit, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig MPI Germany Massachusetts General Hospital, Harvard Medical School Harvard-MGH USA Rensselaer Polytechnic Institute RPI USA Tourette [...] and Psychotherapy, Albert-Ludwigs-University Freiburg With external institutions - International Cooperation partners in the TicGenetics study Rutgers University (Gary Heiman/Jay Tischfield). Children's
Transplantation Human Genetics Anesthesiology and Intensive Care Medicine Psycho-oncology Palliative medicine Comprehensive Cancer Center Hannover (Claudia von Schilling Center) Institute of Clinical Chemistry [...] Department of Radiotherapy and Special Oncology Clinical Department of Nuclear Medicine Institute of Radiology Institute of Pathology Cooperation partners within the MHH Cooperation partners within the MHH [...] to provide you with comprehensive treatment. Thanks to this close cooperation between different institutions, we can offer you as a patient a broad range of diagnostics and therapies that you will only find
case report ". https://pubmed.ncbi.nlm.nih.gov/40938529/ 03.09.2025 Today a project from MHH Human Genetics, MHH Pediatrics, HZI and MHH Nephropathology, among others, was published: "Presentation of patients [...] technology" with Histomography GmbH, Lung Pathology, Institute of Neuroanatomy and Cell Biology, LEBAO and Radiation Protection of the MHH with the Institute of X-ray Physics of the University of Göttingen [...] 2024 Today the paper "Heterozygous variants in the teashirt zinc finger homeobox 3 (TSHZ3) gene in human congenital anomalies of the kidney and urinary tract" was published. Nephropathology was a cooperation
Institute of Molecular Biology Research profile of the department In our institute independent groups address basic questions concerning organ and tissue development and cell differentiation using the [...] mouse as model organism and a variety of modern biochemical, molecular genetic, and transgenic methods and technologies. The institute participates in the following study programs: BSc Biology, Leibniz-University
cell nuclei marked in green, the reticular nucleus of the thalamus. As two recent studies from the Institute of Cellular Chemistry show, a carbohydrate compound of the cell surface, polysialic acid, is essential [...] essential for the development of these nerve fibers. Similar to the mouse model, genetically determined deviations in polysialic acid synthesis and reduced connectivity of the cerebral cortex can also occur [...] in the research report are based on the information provided by the respective Facilities or Institutions. The entry is made without guarantee. The masculine form of all gender-specific descriptions applies
impairs important signaling pathways and leads to human diseases, collectively referred to as ciliopathies. Disruption of motile cilia function in humans causes a subset of ciliopathies known as primary [...] homeostasis. Using the mouse as the animal model of choice and a combination of biochemical, molecular genetic and transgenic methods, we analyze the physiological roles of Notch signaling in different tissues [...] of these genes in mice leads to phenotypes that resemble parts or the entire spectrum of PCD in human patients (e.g. Weidemann et al. 2016, Beckers et al. 2018, 2020, Rachev et al. 2020). Several projects
between the Institute and the Central Animal Laboratory enable biomedical research to be combined with laboratory animal science topics . Examples of this are the establishment of genetic examination methods [...] Research At the Institute of Laboratory Animal Science, we deal with issues relating to animal welfare and the standardization of laboratory animals in line with the 3Rs principle as well as the chara
Compulsory modules Introduction to Data Science (BD P 01) Imaging of biological systems (BD P 02) Human Genetics (BD P 03) Clinical Studies and Biobanking (BD P 04) Introduction to Data Analysis (BD P 05)