approach, in which we combine cell biological, immunological and genetic methods with the use of animal disease models. In our studies we also aim to develop innovative immune-based therapeutic strategies
measurements by tomographic magnetic resonance imaging of the isotope Xe-129 in adipose tissue in a small animal model. By determining absolute temperatures with high precision and good spatial resolution, local
There is a so-called "red hand letter " regarding immunosuppressants such as MMF (Cellcept/Myfortic). Animal experiments have shown a negative influence on sperm. If a male patient wishes to have children,
phenotypic characteristics of primary human alveolar macrophages. These promising results from the animal model suggest that pulmonary transplantation of macrophage precursors could be an effective and
complex mechanisms of human organogenesis in a dish , the HFO model can also be used for replacing animal studies in the process of drug discovery and development such as teratogenicity assessment or drug [...] screen to conduct trials on a number of drug candidates, which in turn could reduce the usage of animals in line with the 3R principles (Replacement, Reduction and Refinement). Collaborators on heart disease
Hetzel T, Kahrass H, Mertz M (2023): Animal research ethics as interaction of research ethics, animal ethics, and (animal protection) law. ALTEX - Alternatives to animal experimentation 40(3), pp. 541-544 [...] (2024): Why Do I Choose an Animal Model or an Alternative Method in Basic and Preclinical Biomedical Research? A Spectrum of Ethically Relevant Reasons and Their Evaluation. Animals 14, 651. doi: 10.3390/ [...] Todorović Z*, Kahrass H, Selter F (2024): Interdisciplinary animal research ethics – challenges, opportunities, and perspectives. Animals 14(19):2896 (* gleichwertiger Beitrag). doi: 10.3390/ani14192896
Kunzmann P (2020): Philosophy of a „good death“ in small animals and consequences for euthanasia in animal law and veterinary practice. Animals 10: 124: DOI 10.3390/ani10010124 2019 Neitzke G (2019): [...] Tom go? An empirical study on intuitions regarding end-of-life decisions in companion animals and humans. Animals 12: 2494. DOI: 10.3390/ani12192494 Neitzke G, Simon A (2022): Clinical ethics consultation
see your child. Can I bring something for my child? Of course. Often the children receive stuffed animals, lucky charms or even a music box as a gift from their parents and relatives. Please take care to
Brodowski then presented the innovations in his field with impressive ultrasound images and 3D animations of prenatal hand and foot malformations. Thanks to high-resolution ultrasound technology, it is
Rabea Hinkel, German Primate Centre, Leibniz Institute for Primate Research, Department of Laboratory Animal Science 10.05.2023 REBIRTH colloquium (1 pm s.t., online lecture) ‘Bioinstructive materials to study