Project management and monitoring Project management Coordination and control of the project and contractors such as test product manufacturers, external monitors, coordination centers abroad, etc. Risk [...] review, error analysis and continuous optimization of project processes Contract, time and budget control Creation and revision of central documents such as the project plan Document management (maintaining

with laminar flow to treat lung failure caused by inhalation trauma. Here, a flow-controlled system is used to control the patient's exhalation and inhalation, thereby reducing the high ventilation pressures [...] the size of the burnt body surface increases, there is also a strong generalized, partly immune-controlled reaction of the organism, the so-called burn disease, which can result in the failure of several

includes technical inspections for old and new systems and the associated legal requirements. With a control room manned 24 hours a day, the TGM ensures the operation of the technical building systems and media [...] areas of the MHH to be supplied and at the same time ensures a rapid response to incidents. The control room also provides the reporting head in the event of major incidents or emergency plan releases [...] expressly encouraged at TGM and is extensively supported. The departments work very closely with the control room (ZLT), which ensures the operation (setting, switching and monitoring of the technical systems)

mycobacteria (CFU) per application is investigated in this phase III, randomized, double-blind, placebo-controlled, multicentre, clinical trial. Efficacy and safety of VPM1002 will be assessed in reducing hospital [...] mycobacteria (CFU) per application is investigated in a phase III, randomized, double-blind, placebo-controlled, multicentre, clinical trial to assess the efficacy and safety in reducing healthcare professionals’ [...] Tobias Welte Department / Institute: Department of Pneumology A randomized, double-blind, placebo-controlled, study evaluating the efficacy and safety of otilimab IV in patients (≥ 70 years) with severe pulmonary

medicine relies on the results of controlled trials and provides the scientific basis for our medical decision-making. However, in order to conduct studies under the most "controlled" conditions possible, there [...] s should still be good at the time of the start of therapy. "Conducting studies under the most controlled conditions possible is important to ensure an objective assessment of the investigational medicinal [...] scientific rationale for medical decision-making. However, in order to conduct studies under the most "controlled" conditions possible, prespecified in- and exclusion criteria must be met by all participating

Equipment Illumina NextSeq 550 10x Genomics Chromium Single Cell Controller Decentralized sequencers Nanodrop ND-1000 spectral photometer Agilent 2100 Bioanalyzer Agilent hybridization oven Agilent Microarray [...] of free capacity and can therefore be arranged for shared use. 10x Genomics Chromium Single Cell Controller The Chromium Single Cell Gene Expression Solution provides a comprehensive, scalable solution for [...] gene expression profiling of hundreds to tens of thousands of cells. The compact, sleek Chromium Controller rapidly and efficiently combines large numbers of partitions with a massively diverse barcode library

immunological and human genetic studies in patients with multisomatoform disorder compared to a healthy control group (in cooperation with Prof. Dr. Gündel, PD Dr. Jäger (Psychosomatics), Prof. Dr. Stuhrmann- [...] postulated that there are significant differences at all these levels compared to an unaffected control group. In addition, the observation of different phenomenological manifestations in different gene [...] 2007), which could be achieved by administering TNF-alpha inhibitors, require clinical placebo-controlled studies. Studies in which TNF-alpha inhibitors are administered as part of an IVRB are particularly

sequencing (mature microRNAs) Microarray-based mRNA expression profiling RNA quality control Genomics DNA quality control Whole genome sequencing Exome sequencing Amplikon sequencing Target-enrichment sequencing [...] with the stakeholders and the ZIMt) DNA sequencing data processing and analysis (including quality control, trimming, mapping, and filtering) Long read analyses for bacterial whole genomes, metagenomics,

Clinical Department of Neurology: Amyotrophic lateral sclerosis (ALS): ROCK-ALS: a Randomized, Placebo-Controlled, Double-Blind Phase IIa Trial of Safety, Tolerability and Efficacy of the Rho Kinase (ROCK) Inhibitor [...] in ALS. ClinicalTrials.gov Identifier: NCT03505021 ORARIALS-01: A Phase III, Randomized, Placebo-Controlled Trial of Arimoclomol in Amyotrophic Lateral Sclerosis. Arimoclomol is a chaperone activator designed [...] gov Identifier: NCT03491462 Post-polio syndrome: Multicenter, prospective, randomized, placebo-controlled, double-blind, parallel-group study to evaluate the efficacy and safety of intravenous immunoglobulin

Engineering Act. Authenticity control of the genetic background: microsatellite markers (SSLP), single nucleotide polymorphisms (SNP), monoclonal antibodies (mAbs) Genotype control of individual mutations: