Saborowski uses a mouse model, for example, to investigate the influence of certain genetic changes on a tumor. Is the genetic modification suitable as a target structure for drug therapy approaches? Can premature [...] Mainz for almost 20 years - under his aegis it became an internationally leading Facilities or Institutions for the treatment of malignant blood and tumor diseases and a center for stem cell transplantation [...] international research funding organizations and as a scientific advisor in major German research institutions such as the German Cancer Research Center in Heidelberg, the GSF Research Center for Environment

have a significant influence on the differentiation and function of T cells. A study from the Institute of Infection Immunology at Twincore (Berod et al. Nat Med. 2014 20:1327-33) was able to show that [...] the myxobacterial agent soraphen A not only very effectively inhibits the development of murine and human inflammatory T cells, but also simultaneously favors the development of anti-inflammatory regulatory [...] in the research report are based on the information provided by the respective Facilities or Institutions. The entry is made without guarantee. The masculine form of all gender-specific descriptions applies

MZP Cardiomyocytes from human induced pluripotent stem cells as a cellular model for hypertrophic cardiomyopathy Researc h focus The focus of our research is the analysis of human induced pluripotent stem [...] β-Myosin heavy chain isoform-expressing myofibrils within human ESC-derived cardiomyocytes recapitulate the contractile features of adult human ventricular myofibrils?, J. Muscle Res. Cell. Motil., 2017 [...] (cMyBP-C). Mutations in cMyBP-C are besides mutations in beta-cardiac myosin (MyHC) the most frequent genetic cause for hypertrophic cardiomyopathy (HCM). HCM is a severe disease of the heart, which is mostly

Sammlung/Foto:Karin Kaiser/MHH The Institute of Functional and Applied Anatomy organizes the internship in macroscopic anatomy (dissection course) for students of Human medicine. Only students enrolled at

report shows a method for capturing the three-dimensional shape of 138 human inner ears using µCT and corrossion technology. The human inner ear is surprisingly variable in its microanatomy and does not [...] MHH researchers were able to use this data to precisely mathematically model the geometry of the human inner ear. The results were used for the development of a new cochlear implant electrode from Advanced [...] carried out in collaboration with the "Advanced Bionics European Research Center", GmbH, and the Institute of Biometry at the MHH. Until the Research Information System (FIS) is introduced, no research reports

for Paediatric Gastroenterology and Hepatology), Prof. Dr. med. Frank Wacker (Radiology Centre, Institute of Diagnostic and Interventional Radiology) work closely with other medical departments on an i [...] cancer, endoscopy, sonography and interventional radiology as well as the latest procedures for genetic diagnostics of congenital liver diseases. Innovative therapy concepts such as gene therapy for m

unit (IFB-Tx funded project) Institute for Microbiology Institute for Legal Medicine Institute for Psychosomatic disorders Institute for Experimental Neurosurgery Institute for Clinical Chemistry Lab for [...] for Molecular Neuroscience External Institute for Psychiatry from Minden- Lübecke Clinics for Addiction Research, Central Institute Mannheim Paracelsus Medical Private University, Nuremberg Awards, Grants [...] Addiction counts among the most common psychiatric disorders. A complex combination of biological, genetic, epigenetic, social, and psychological factors impacts patients' onset and progress. Our group i

Institute for Ethics, History and Philosophy of Medicine Head of Institute Prof. Dr. med. Dr. phil. Sabine Salloch Office: Britta Sander , phone: +49 511 532-4278, fax: +49 511 532-165650, Email Teaching [...] Teaching The Institute of Ethics, History and Philosophy of Medicine is currently involved in six degree programs at the MHH. In addition, staff members of the Institute are engaged in the advanced training [...] please refer to ILIAS . Dr. med. Gerald Neitzke is the teaching coordinator. Human Medicine (Staatsexamen) The Institute offers the module “History, Theory, and Ethics of Medicine” which addresses fundamental

Epigenetic and Biological Subgroups of Glioblastoma. Cancer Cell. 2012 Oct 16;22(4):425-37. Institute of Human Genetics Sorted by year (most recent first) and then alphabetically by first author FÖRSTER A, BRAND [...] KRATZ CP, STANULLA M, CAVÉ H. Genetic predisposition to acute lymphoblastic leukemia: Overview on behalf of the I-BFM ALL Host Genetic Variation Working Group. Eur J Med Genet. 2016 Mar;59(3):111-5. doi: [...] MALKIN D, GAJJAR A, KORBEL JO, PFISTER SM. Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort. Lancet

explains Professor Dr. Britta Eiz-Vesper, immunologist at the MHH Institute for Transfusion Medicine and Transplant Engineering. As the institute is not only one of Germany's leading manufacturing sites for [...] Neurophysiology, the Institute of Transfusion Medicine and Transplant Engineering, the Department of Paediatric Haematology and Oncology, the Department of Pneumology and the Institute of Diagnostic and [...] all people worldwide without most of them even noticing it. But once it has entered the body, the genetic material of the pathogen remains dormant. If the immune system is weakened or shut down by a serious