organ constituting over 650 muscles accounting for approximately 40% of total body mass and up to 30% of basal energy expenditure. The skeletal muscle displaying a characteristic striated pattern is an [...] cancer cachexia, prevalent in nearly 80% of cancer patients with reported mortality rate in more than 30% patients. The major focus of our group is understand how SUMO (Small Ubiquitin-like Modifier)-mediated [...] Dikic I, Mittelbronn M, Behrends C (2017) Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. Elife 6 Nayak A , Muller S (2014) SUMO-specific
Levels and Correlation With Pulse Wave Velocity After Kidney Transplantation. Front Cardiovasc Med. 2021;8:692213. doi: 10.3389/fcvm.2021.692213 *Authors contributed equally. Stocklassa T, Borchert-Mörlins B [...] Organ Damage After Renal Transplantation: A Single-Center Cohort Study. J Womens Health (Larchmt). 2021;30:1352-61. *Authors contributed equally. Melk A*, Schmidt BMW*, Geyer S, Epping J. Sex disparities in
Leukocyte telomere length correlates with hypertrophic cardiomyopathy severity. Sci Rep. 2018; 8:11227-018-29072-8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060137/ de Gonzalo-Calvo D, Cediel G, Bar C [...] L, Bar C, Thum T. Long non-coding RNAs: At the heart of cardiac dysfunction? Front Physiol. 2019;10:30. https://www.ncbi.nlm.nih.gov/pubmed/30761015 Jung M, Dodsworth M, Thum T. Inflammatory cells and their [...] ST-segment-elevation myocardial infarction: A cardiovascular magnetic resonance study. Sci Rep. 2018; 8:15115-018-33491-y. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181905/ Derda AA, Pfanne A, Bar C,
Hopfner KP. Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin. EMBO J. 30, 2153-2166. Breitsprecher D, Kiesewetter AK, Linkner J, Vinzenz M, Stradal [...] Characterization of Ubiquitin-Like Core Autophagy Protein ATG12 in Dictyostelium discoideum. Cells. 8(1). Marinović M, Mijanović L, Šoštar M, Vizovišek M, Junemann A, Fonović M, Turk B, Weber I, Faix J [...] MF, Sixt M, Käs J, Faix J, Rottner K. FMNL formins boost lamellipodial force generation. Nat Commun. 8, 14832. Dang I, Linkner J, Yan J, Irimia D, Faix J, Gautreau A. The Arp2/3 inhibitory protein Arpin
performance 10 years after approval: a systematic analysis. Naunyn Schmiedebergs Arch Pharmacol. 2025 May 8. doi: 10.1007/s00210-025-04178-9. Epub ahead of print. Dulle M, Seifert R . Ivermectin repurposing for [...] ward as an example. Naunyn Schmiedebergs Arch Pharmacol. 2025 Mar 6. doi: 10.1007/s00210-025-03892-8. Epub ahead of print. Bargsten FE, Seifert R . Devil's claw (Harpagophytum procumbens): is the buzz [...] current clinical studies. Naunyn Schmiedebergs Arch Pharmacol. 2024. doi: 10.1007/s00210-024-03210-8. Epub ahead of print. Arning A, Seifert R . Insufficient correctness of package inserts for psychotropic
of related research fields present current data and projects. 22.01.2024 REBIRTH Special Lecture (12:30 pm, lecture hall Q) ‘The future is here! The next generation of AAV vector as a foundation of cell [...] Center for Lung Research BREATH and the REBIRTH Cluster of Excellence. It will take place from May 8-10 in the “Schloss Herrenhausen” in Hannover. The topics include regeneration, transplantation, stem [...] engineering, imaging, ethics in regenerative science, and patients’ view on regenerative science. Over 30 international and national leaders in these fields will present to an expected audience of up to 400
caregiving responsibilities and the need for care (cf. § 16 (2) Study Regulations for Human Medicine; § 8 (5) No. 1 Study Regulations for Dental Medicine MHH). Please contact the Dean's Office or the Student [...] Students lose their eligibility for the favorable student health insurance upon reaching the age of 30. The MDK Reform Act has removed the limitation up to the 14th semester and added an exception, allowing [...] within seven days (at least 2 days per week). The professional activity is limited to a maximum of 30 hours per week. Studying does not count as professional activity, which means that students can receive
nodular inflammatory foci by cooperation of interferon-gamma expressing CD4 and CD8 T cells. PLoS Pathog. 2018 Aug 28;14(8):e1007252. doi: 10.1371/journal.ppat.1007252. eCollection 2018 Aug. PubMed PMID: [...] retention and negative selection of CD8 positive thymocytes as well as T cell differentiation to follicular helper cells in Peyer's Patches. Immunobiology. 2013 Feb;218(2):152-8. doi: 10.1016/j.imbio.2012.02.010 [...] retention and negative selection of CD8 positive thymocytes as well as T cell differentiation to follicular helper cells in Peyer's Patches. Immunobiology. 2013 Feb;218(2):152-8. doi: 10.1016/j.imbio.2012.02.010
glutamate receptors in spinal motor neurons of SOD1 mice. J Neurol Sci. 2005 Nov 15; 238(1-2):25-30 Epub 2005 Aug 8. Jungnickel J, Klutzny A, Guhr S, Meyer K, Grothe C. Regulation of neuronal death and calcitonin [...] Tudorache I, Nolte I, Wacker F, Hilfiker A, Hoeffler K, Haverich A, Cebotari S. Eur Surg Res. 2022 Feb 8;63(4):219-26. doi: 10.1159/000522478 . Specification of CNS macrophage subsets occurs postnatally in [...] Regen Med . 2020. in press https://doi.org/10.1002/term.3036 Muscle overexpression of Klf15 via an AAV8-Spc5-12 construct does not provide benefits in spinal muscular atrophy mice. Ahlskog N, Hayler D, Krueger
Tyrosine Phosphorylation of CD2AP Affects Stability of the Slit Diaphragm Complex. J Am Soc Nephrol 30, 1220-1237. Eschenburg, S. , Reubold, T.F. (2018) Modulation of dynamin function by small molecules [...] serine protease--crystal structure of the complex of a partially modified proteinase K with mercury at 1.8 A resolution. Indian J. Biochem. Biophys. 38 , 298-302. Betzel, C., Gourinath, S., Kumar, P., Kaur, [...] K., Kabsch, W., Amrhein, N. (2000). Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the antibiotic target MurA. Proc. Natl. Acad. Sci. USA 97