Jordans S, Dilloo D. J Cell Mol Med 2022;26(23):5832-5845 DOI: 10.1111/jcmm.17604 Polarization of human iPSC-derived macrophages directs their immunological response to secondary pro-inflammatory stimuli. Schinke [...] -438 DOI: 10.1007/s00109-020-02020-8 Efficient Genetic Safety Switches for Future Application of iPSC-Derived Cell Transplants. Dahlke J, Schott JW, Vollmer Barbosa P, Klatt D, Selich A, Lachmann N, Morgan [...] Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages Alexandra Lipus, Ewa Janosz, Mania Ackermann, Miriam Hetzel, Julia Dahlke, Theresa Buchegger

Motil. 2025 Feb 13. doi: 10.1007/s10974-025-09690-2. Online ahead of print. PubMed Patient-specific hiPSC-derived cardiomyocytes indicate allelic and contractile imbalance as pathogenic factor in early-stage

J. Mol. Sci. 2025 , 26 (1), 218; https://doi.org/10.3390/ijms26010218 , PubMed Patient-specific hiPSC-derived cardiomyocytes indicate allelic and contractile imbalance as pathogenic factor in early-stage [...] Nature . 2021 May 26. doi: 10.1038/s41586-021-03573-5. Online ahead of print. PubMed Generation of two iPSC clones (MHHi021-A and MHHi021-B) from a patient with hypertrophic cardiomyopathy with p.Arg723Gly mutation [...] 31;11(1):633.doi: 10.1038/s41467-020-14349-2., PubMed 2019 Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture

animal and cell culture models as well as patient samples including induced pluripotent stem cells (iPSC) and post mortem brain tissue, and employ a broad spectrum of state-of-the-art molecular testing methods

human induced pluripotent stem cell (hiPSC) line, which enables modulation of telomerase activity and telomere length at will. Furthermore utilizing the power of hiPSC differentiation protocols, these cells [...] division and proliferation July 2025 We have developed a novel human induced pluripotent stem cell (hiPSC) reporter line expressing cyclinB1-eGFP, enabling live tracking of proliferating cells across multiple [...] cardiomyocyte proliferation August 2024 We have developed a human induced pluripotent stem cell (hiPSC) fluorescent reporter line to track and sort replicating cardiomyocytes, overcoming the limitations

the early detection of cholangiocellular carcinoma in patients with primary sclerosing cholangitis (PSC)" 26.05.2025 Sophie Engelskircher AG Wedemeyer/Woller "Long-Hep-C: Persistent changes in the immune

Goethe R, Jonigk D , Kalinke U, Boisson-Dupuis S, Casanova J-L , Bustamante J, Lachmann N. Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway . Cells. 2020 Feb 19;9(2):483 [...] Dahlmann J, Hegermann J, Werlein C , Jonigk D , Haverich A, Martin U, Olmer R, Gruh I. Dual Function of iPSC-Derived Pericyte-Like Cells in Vascularization and Fibrosis-Related Cardiac Tissue Remodeling In Vitro

Jun 27;15(1):20331. doi: 10.1038/s41598-025-07167-3. PMID: 40579400; PMCID: PMC12205068. Exploring hiPSC-CM replacement therapy in ischemic hearts Cipriano G, Thum T, Weber N. Basic Res Cardiol. 2025 Aug [...] Dec 30;26(1):218. doi: 10.3390/ijms26010218. PMID: 39796086; PMCID: PMC11720517. Patient-specific hiPSC-derived cardiomyocytes indicate allelic and contractile imbalance as pathogenic factor in early-stage

Verjans GMGM, Schmidt M, Kispert A, Cantz T, Gomis A, Wegner F, Viejo-Borbolla A. Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings

Fenske A , Jang MS, Jirmo AC, Abeln M, Hansen G, Lachmann N (2024). Standardized generation of human iPSC-derived hematopoietic organoids and macrophages utilizing a benchtop bioreactor platform under fully [...] Epub 2021 May 8. PMID: 33975020 Dettmer R , Niwolik I, Mehmeti I, Jörns A, Naujok O (2021). New hPSC SOX9 and INS Reporter Cell Lines Facilitate the Observation and Optimization of Differentiation into [...] Stalp JL, Glage S, Abeln M , Zweigerdt R, Munder A, Viemann D, Ackermann M, Lachmann N (2021). Human iPSC-derived macrophages for efficient Staphylococcus aureus clearance in a murine pulmonary infection model