Flörkemeier, T.*, Hoffmann, A.* # (2020) : Heparin Anticoagulant for Human Bone Marrow Does Not Influence In Vitro Performance of Human Mesenchymal Stromal Cells. Cells;9(7):E1580 Winkel, A., Jaimes, Y. [...] meaningful, reproducible and predictable in the future. To this end, we investigate the function of human mesenchymal stem cells under normal and inflammatory conditions and develop novel isolation and c [...] students. Signaling pathways in regeneration: A molecular mechanism for tendon cell formation. Genetically modified MSCs differentiated in vitro into tendon-like cells. Implantation in vivo enabled cel
Publications Publications of the Institute of Clinical Biochemistry since 2019 and the former Institute for Cellular Chemistry since 2003 sorted by year and first author. Publications 2025 Carneiro P [...] G, Guengoer C, Wagener C, Schumacher U, Lange T (2020). Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions. Glycobiology. 2020 [...] S, Fenske A , Jang MS, Jirmo AC, Abeln M, Hansen G, Lachmann N (2024). Standardized generation of human iPSC-derived hematopoietic organoids and macrophages utilizing a benchtop bioreactor platform under
Institute of Toxicology Director: Prof. Dr. Dr. Harald Genth (acting) Postal address: Hannover Medical School Institute of Toxicology - OE 5340 Carl-Neuberg-Straße 1 … Welcome to the Institute of Toxicology [...] Thank you to Professor Ingo Just, Director of our Institute from July 1, 2000 to March 31, 2025: E-Mail Prof. Dr. med. Ingo Just, Director of the Institute of Toxicology and Dean of Studies, concluded his [...] (2015-2023), and as an expert for the Institute for Medical and Pharmaceutical Examination Questions in Mainz (IMPP, 2002-2008). We sincerely thank our institute director and friend, Prof. Ingo Just, for
Schweitzer N, Vogel A, Kreipe H , Lehmann U : Concordant hypermethylation of intergenic microRNA genes in human hepatocellular carcinoma as new diagnostic and prognostic marker. Int J Cancer 2013; 133(3): 660-670 [...] Wilhelm J, Chakraborty T, Warnecke G, Gottlieb J, Padberg W, Grau V: A relevant experimental model for human bronchiolitis obliterans syndrome. J Heart Lung Transplant 2013; 32(11): 1131-1139 Bachmann S, Panzica [...] Ganser A, Heuser M: Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML. Blood 2013; 122(16): 2877-2887 Christgen M, Geffers R, Kreipe H, Lehmann U : IPH-926 lobular
COVID-19 pandemic is a very dynamic event. Recommendations and instructions from the Robert Koch Institute and the authorities may change at short notice and may go beyond or replace the recommendations [...] SARS-CoV-2 pandemic is a very dynamic event. Recommendations and instructions from the Robert Koch Institute (RKI) and other health authorities may change at short notice and therefore temporarily deviate [...] Patients with limited production or efficacy of type I interferons Possibly other individual genetically defined immunodeficiencies The risk of severe SARS-CoV-2 infection is probably higher for the patient
Kubis Immunochemical evidence for a unique GPI-anchored carbonic anhydrase isozyme in human cardiomyocytes. human cardiomyocytes. Am.J.Physiol.Heart Circ.Physiol. 278: H1335-H13442000. Meissner, J.D., [...] produced mutants in cell culture and by studying rhesus and aquaporin-1-deficient erythrocytes from human and mouse blood. Plasticity of skeletal muscle Different types of stress, such as continuous stress [...] C.D. Fenske, W.S. Sly, N.D. Carter and G. Gros Localization of carbonic anhydrase IV in rat and human heart muscle. J.Histochem.Cytochem. 46: 855-861, 1998. Wetzel, P. and G. Gros Inhibition and kinetic
close cooperation with all the world's leading research institutes and manufacturers of botulinum toxin drugs as well as leading clinical institutions for movement disorders. Special research focuses are [...] botulinum toxin therapy, duodopa pumps, apomorphine pumps, baclofen pumps, epidemiological and genetic issues, psychogenic movement disorders and complex pharmacotherapies. The area of movement disorders
developmental psychology Research assistant in developmental psychology 1986-1990 Diabetes Research Institute Düsseldorf¸ research associate Research associate in psychodiabetology 1990-2023 Hannover Medical [...] developmental psychology Research assistant in developmental psychology 1986-1990 Diabetes Research Institute Düsseldorf¸ research associate Research associate in psychodiabetology 1990-2023 Hannover Medical [...] parents of children with congenital rare diseases, e.g. MPS, PKU, cystinosis, thyrosinemia or genetically increased risks, e.g. type 1 diabetes Training of diabetologists, diabetes consultants and diabetes
that activate and regulate the infection-induced immune response. In addition, we explore the (epi) genetic background as well as the molecular and metabolic processes of infection-associated immune responses [...] intestinal immune responses under in vivo conditions. We use established as well as newly generated genetic mouse models that allow for the deletion of the key metabolic enzymes in specific immune- and non-immune [...] potential of pharmacologic modulation of metabolic pathways and translate these findings into the human system. It has been a long-standing focus of our research group to analyze the immune response in
difficult situation and beyond the period of hospitalization, we have joined forces with the Institute for Human Resources in Freiburg and the "Kleine Herzen Hannover" association to set up a crisis intervention [...] of participants is limited to 15 per course. Highly qualified training is provided by the Institute for Human Resources (IHR, Freiburg), which works closely with the DRK. The course content will include [...] situations. However, due to the lack of trauma psychologists or other counseling facilities or Institutions, this need cannot be met. In order to provide professional psychological and social support to