to personal reasons. Jana van Luttikhuizen NETHERLANDS Supervisor: Prof. Dr. Doris Steinemann, Human Genetics, OE 6300, Project: Genomic copy number variations associated with response and resistance to [...] : Prof. Dr. Christine Falk, IFB-Tx, OE 8889, Project: T and NK cell-mediated immune responses of human lung transplant recipients in vivo - impact on the development of transplant arteriosclerosis. Final [...] therapy. Final exam June 2020. Michelangelo Marasco ITALY Supervisor: Prof. Dr. Teresa Carlomagno, Institute for Organic Chemistry / BMWZ, Leibniz Universität Hannover, Project: Structural basis of the activation

& Bucan, V. (2019). Down-Regulation of MHC Class I Expression in Human Keratinocytes Using Viral Vectors Containing US11 Gene of Human Cytomegalovirus and Cultivation on Bovine Collagen-Elastin Matrix [...] antifreeze medium. Freezing and storage take place at the Hannover Unified Biobank (https://www.mhh.de/institute-zentren-forschungseinrichtungen/hannover-unified-biobank-hub). This will provide an alternative [...] donor cells are specifically manipulated. The feasibility of this has already been demonstrated on a genetic basis. The next step is now the transfer to the protein level. This project is funded by the VHV

recently become known that the development of a tumor and its progression are not only caused by genetic changes within the cell, but that epigenetic features such as histone acetylation are also disturbed [...] es are significantly overexpressed in HCC. It is known that alteration of histone acetylation in human tumor cells leads to altered transcription of genes and miRNAs. Using cell culture work and modern [...] in the cell and possibly find targets for new therapeutic options. Our main areas of research In human tumor cells, the chromatin structure of further genomic regions is altered by epigenetic modification

511 532-4176 Email address: allgemeinmedizin@mh-hannover.de H Human Genetics Prof. Dr. Nataliya Di Donato ►To the Institute of Human Genetics Head: Professor Dr. Nataliya Di Donato Contact: +49 511 532-4523 [...] Heinrich Lanfermann About the Institute of Diagnostic and Interventional Neuroradiology Institute Director: Prof. Dr. med. H. Lanfermann Office: Ms. F. Özanadolu Institute of Diagnostic and Interventional [...] med. Roland Seifert About the Institute of Pharmacology Head: Prof. Dr. med. Roland Seifert Institute secretariat: Jana Nissen Assistant to the Director of the Institute Contact: Tel: +49 511 532-2805/2806

die on the waiting list for a human donor organ. In order to counteract the underlying shortage of organ donors, efforts are being made to provide animal organs for human transplant patients. Efforts to [...] transfer of animal tissue or organs to a human recipient is possible without any problems, provided that the transplant corresponds in size, shape and physiology to the human structure to be replaced. This is [...] of necessary as well as target-oriented genetic modifications of the donor pigs 2) The establishment of suitable ex vivo perfusion models to analyze the human-relevant immune potential of pig lungs 3)

Projects Phylogeny and Function of Vγ9Vδ2 T cells: Human vs. Camelids (Prof. Dr. Thomas Herrmann) Plasticity of human gamma/delta T cells: (Epigenetic) Modulation by Vitamin C (Prof. Dr. Dietrich Kabelitz) [...] mechanism of γδ TCR activation, in order to enhance tumour killing (Prof. Dr. Wolfgang Schamel) Genetically engineered chicken models: novel tools to investigate lymphocyte development and function (Prof

AG Prof. Dr. A. Kispert Research Our research focuses on the genetic control mechanisms of vertebrate development using the mouse as a model organism. In particular, we want to better understand the cellular [...] inner ear and especially the kidney and ureter. Our work also aims to better understand congenital human diseases such as cardiac valve septal defects, urinary tract anomalies and hearing loss. To this end [...] could provide the basis for the resumption of development programs for regenerative approaches in human diseases. A major focus of our molecular work is the analysis of signaling pathways (including Hedgehog

are welcome Lecture "Molecular Genetics" This lecture is for: Students on the Biology (Bsc) study programmes and is offered as part of the elective module Molecular Genetics. The lecture is followed by an [...] science": The lecture series is aimed at students of natural science study programs, students of human medicine and dentistry as well as all employees of the MHH who want to participate in animal experiments [...] 2025 Thu G Species-specific handling and application methods 20.11.2025 Thu G Blood collection and humane killing of laboratory animals Experimental animals 27.11.2025 Thu D Preoperative care, anesthesia

Molecular Human Genetics (BCM WP 31) Copyright: Trulley, Philipp / Zellbiochemie / MHH Competencies After successfully completing the module, students will be able to model and solve simple problems relating

first cloned 13 genetically very different HCV variants. These viruses belong to five of the eight most widespread HCV genotypes and therefore cover a very broad spectrum of the genetic diversity of the [...] These NBTs cannot be predicted from genetic sequence comparisons, but represent different functional properties of the viral envelope proteins with respect to human antibodies (Bankwitz et al. Gut 2021) [...] mechanisms of protection and for prioritization of vaccines. Here, we used a unique collection of human specimens and HCV strains to develop HCV reference viruses for quantification of neutralizing antibodies